EGFR/KRAS/BRAF Mutations in Primary Lung Adenocarcinomas and Corresponding Locoregional Lymph Node Metastases

K Schmid, N Oehl, F Wrba, R Pirker, C Pirker… - Clinical Cancer …, 2009 - AACR
… In 6 of 7 cases with an EGFR mutation and in 25 of 36 cases with a KRAS mutation, we
found a discordant mutational status in the primary tumor and the corresponding lymph node …

EGFR and KRAS mutations in ALK-positive lung adenocarcinomas: biological and clinical effect

N Sahnane, M Frattini, B Bernasconi, F Zappa… - Clinical Lung Cancer, 2016 - Elsevier
… the clinical outcomes of patients with lung adenocarcinoma (ADC), which … Mutation analysis
of the EGFR and KRAS genes was performed in all 42 ALK-positive tumors. EGFR mutations

EGFR, KRAS, BRAF and ALK gene alterations in lung adenocarcinomas: patient outcome, interplay with morphology and immunophenotype

A Warth, R Penzel, H Lindenmaier… - European …, 2014 - Eur Respiratory Soc
KRAS mutations were prevalent in male smokers, while EGFR mutations were associated
with female sex, nonsmoking and lepidic as well as micropapillary growth patterns. TTF1 …

KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib

W Pao, TY Wang, GJ Riely, VA Miller, Q Pan… - PLoS …, 2005 - journals.plos.org
… First, they extend previous data from our group and others showing that lung adenocarcinomas
containing EGFR mutations are associated with sensitivity to gefitinib or erlotinib (17 of …

Associations between the IASLC/ATS/ERS lung adenocarcinoma classification and EGFR and KRAS mutations

TD Clay, PA Russell, H Do, V Sundararajan, M Conron… - Pathology, 2016 - Elsevier
We sought to investigate the frequency of mutations in epidermal growth factor receptor (EGFR)
and Kirsten-RAS (KRAS) by each pathological subtype for patients with resected …

[HTML][HTML] Spectrum of LKB1, EGFR, and KRAS mutations in chinese lung adenocarcinomas

B Gao, Y Sun, J Zhang, Y Ren, R Fang, X Han… - Journal of thoracic …, 2010 - Elsevier
EGFR mutations and KRAS mutations were … lung adenocarcinomas is still scant. Herein,
we report on the spectrum of LKB1 mutations and their relationship with EGFR and KRAS

Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications

CC Wu, HY Hsu, HP Liu, JWC Chang… - … Journal of the …, 2008 - Wiley Online Library
… status for each patient and to compare it with the EGFR mutation status, EGFR-TKI sensitivity,
mutation rates of the KRAS and EGFR genes among patients with lung adenocarcinoma in …

Association between the novel classification of lung adenocarcinoma subtypes and EGFR/KRAS mutation status: A systematic literature review and pooled-data …

…, J He, AME Lung Cancer Collaborative Group - European Journal of …, 2019 - Elsevier
… association of EGFR/KRAS mutation status with histological subtypes of lung adenocarcinoma
(LAC) … We found that EGFR mutations are more common in patients with resected lepidic …

Comparison of CT radiogenomic and clinical characteristics between EGFR and KRAS mutations in lung adenocarcinomas

J Lv, H Zhang, J Ma, Y Ma, G Gao, Z Song, Y Yang - Clinical radiology, 2018 - Elsevier
… year-old male patient with EGFR mutation (+) lung adenocarcinoma shows pneumonic-type …
pathology was lung adenocarcinoma, the incidence of EGFR or KRAS gene mutations that …

Clinicopathological features of lung adenocarcinoma with KRAS mutations

S Kakegawa, K Shimizu, M Sugano, Y Miyamae… - Cancer, 2011 - Wiley Online Library
… The bronchioloalveolar carcinoma (BAC)/adenocarcinoma … of which 64 had EGFR mutations
and 22 had KRAS mutations. The … 12 had EGFR mutations and 9 had KRAS mutations. The …