Mechanisms of disease: pathogenesis of nonalcoholic fatty liver disease

AJ Sanyal - Nature clinical practice Gastroenterology & hepatology, 2005 - nature.com
… Nonalcoholic fatty liver disease (NAFLD) is characterized by the presence of predominantly
macrovesicular hepatic steatosis. Pathogenesis is linked to INSULIN RESISTANCE and the …

Nonalcoholic fatty liver disease: pathogenesis and disease spectrum

T Hardy, F Oakley, QM Anstee… - … : mechanisms of disease, 2016 - annualreviews.org
liver dysfunction in the Western world and is increasing owing to its close association with
obesity and insulin resistance. NAFLD represents a spectrum of liver disease … and liver failure. …

Alcoholic liver disease: pathogenesis and new therapeutic targets

B Gao, R Bataller - Gastroenterology, 2011 - Elsevier
liver disease (ALD) is a major cause of chronic liver disease … Abuse and Alcoholism showed
that liver cirrhosis was the 12th … Early work on the pathogenesis of the disease focused on …

Genetics of liver disease: immunogenetics and disease pathogenesis

PT Donaldson - Gut, 2004 - gut.bmj.com
… ; and (c) provide insight into the pathogenesis of these diseases. Of these three objectives the
last … of chronic liver disease is beginning to inform the debate about disease pathogenesis. …

[HTML][HTML] Alcoholic liver disease: pathogenesis and current management

NA Osna, TM Donohue Jr… - Alcohol research: current …, 2017 - ncbi.nlm.nih.gov
… by excessive liver scarring, vascular alterations, and eventual liver failure. … liver disease
because a number of disease modifiers exacerbate, slow, or prevent alcoholic liver disease

Nonalcoholic fatty liver disease: pathology and pathogenesis

DG Tiniakos, MB Vos, EM Brunt - … : Mechanisms of Disease, 2010 - annualreviews.org
Nonalcoholic fatty liver disease (NAFLD) is recognized as the leading cause of chronic liver
disease in adults and children. NAFLD encompasses a spectrum of liver injuries ranging …

Alcoholic liver disease: pathogenesis and new targets for therapy

J Altamirano, R Bataller - Nature reviews Gastroenterology & …, 2011 - nature.com
liver disease (ALD) is a major cause of morbidity and mortality worldwide. The spectrum of
disease ranges from fatty liver … cause of end-stage liver disease that requires transplantation. …

Non-alcoholic fatty liver disease pathogenesis: the present and the future

S Petta, C Muratore, A Craxi - Digestive and Liver Disease, 2009 - Elsevier
… The pathogenesis of non-alcoholic fatty liver disease is not entirely understood, and even …
pathogenetic key, many other factors are implicated in both liver fat accumulation and disease

Nonalcoholic fatty liver disease: pathogenesis and the role of antioxidants

K Mehta, DH Van Thiel, N Shah, S Mobarhan - Nutrition reviews, 2002 - academic.oup.com
… Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of liver injury ranging …
cause of progressive liver fibrosis and can develop into cirrhosis. NAFLD and nonalcoholic ste…

Oxidative stress as a critical factor in nonalcoholic fatty liver disease pathogenesis

S Spahis, E Delvin, JM Borys, E Levy - Antioxidants & redox …, 2017 - liebertpub.com
… in NAFLD/NASH patients (86, 148, 165) (Table 1), and their high concentrations are associated
with the intensity of liver disease (… in the pathogenesis of non-alcoholic fatty liver disease. …