… stress and alcoholic fatty liver, effectively alleviate the liver damage caused by alcohol and
… and liver regeneration promoting effect of IL-22 suggests the therapeutic potential of IL-22 in …

… levels of IL-22 receptor 1 and IL-… 22 in the development progression of liver disease of
different etiologies. It is focused mainly on the IL-22 intracellular signaling and its influence on liver …

… In this study, IL-22 was inversely correlated with liver inflammation and fibrosis stages,
determined by liver histology, whereas the intra-hepatic expression of IL-17 showed a positive …

… chronic liver diseases, including hepatitis B and C. In this report, we demonstrate a strong
correlation between IL-22 expression in the liver with active, inflammatory human liver disease…

… Identification of processes that lead to deterioration of liver … Interleukin (IL)-22 is among newly
identified parameters of … and translational research on liver injury and inflammation [2]. This …

… liver[1], this suggests that rmIL-22 treatment ameliorates liver fibrosis by targeting HSCs in
a murine model of CCl 4 -induced liver … that rmIL-22 not only reduced liver inflammation, but …

… liver regeneration and hepatocyte proliferation in both conditions in vivo or in vitro. IL-22 was
found to control the process of liver inflammation in … in inhibition of liver inflammation and, …

… ‐cell‐mediated chronic liver inflammation and fibrosis, blockade of IL‐22 attenuated hepatic
… and liver inflammation and fibrosis progression. In vitro treatment with IL‐22 stimulated …

… anti-inflammatory functions. Herein, we provide evidence that during inflammation, IL-22 played
… Hepatocytes from mice deficient in IL-22 were highly sensitive to the detrimental immune …

… Herein, we show the therapeutic efficacy of recombinant IL-22 in APAP-induced liver injury.
IL-22 application was associated with amelioration of histologic necrosis, reduction of serum …