[HTML][HTML] Prognostic impact of KRAS mutation subtypes in 677 patients with metastatic lung adenocarcinomas

AY Helena, CS Sima, R Shen, S Kass, J Gainor… - Journal of thoracic …, 2015 - Elsevier
… depending on KRAS mutation subtype. To better understand the impact of KRAS mutation
subtype, we analyzed data from 677 patients with KRAS mutant metastatic lung cancer. …

Association between the novel classification of lung adenocarcinoma subtypes and EGFR/KRAS mutation status: A systematic literature review and pooled-data …

…, J He, AME Lung Cancer Collaborative Group - European Journal of …, 2019 - Elsevier
… This study aims to determine the association of EGFR/KRAS mutation status with histological
subtypes of lung adenocarcinoma (LAC) based on the IASLC/ATS/ERS classification. …

Characterization of KRAS mutation subtypes in non–small cell lung cancer

J Judd, N Abdel Karim, H Khan, AR Naqash… - Molecular cancer …, 2021 - AACR
… In 2015, Skoulidis and colleagues described three major subsets of KRAS-mutant lung
adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities by …

The prevalence and prognostic significance of KRAS mutation subtypes in lung adenocarcinomas from Chinese populations

D Zheng, R Wang, Y Zhang, Y Pan… - OncoTargets and …, 2016 - Taylor & Francis
… of KRAS mutation in patients with lung adenocarcinoma in an Asian ethnic group – to identify
the prevalence of KRAS mutation … analyze their survival with other types of gene mutations. …

Impact of KRAS mutation subtype and concurrent pathogenic mutations on non-small cell lung cancer outcomes

JV Aredo, SK Padda, CA Kunder, SS Han, JW Neal… - Lung Cancer, 2019 - Elsevier
… the effects of KRAS mutation subtypes and concurrent pathogenic mutations on overall …
metastatic KRAS-mutant lung adenocarcinoma demonstrated no difference in OS based on …

[HTML][HTML] Characteristics and outcomes of patients with metastatic KRAS-mutant lung adenocarcinomas: the lung cancer mutation consortium experience

B El Osta, M Behera, S Kim, LD Berry, G Sica… - Journal of thoracic …, 2019 - Elsevier
… , few studies have thoroughly analyzed the biological impact of various KRAS mutation
subtypes and their impact of disease behavior and clinical outcomes. In a large series of 677 …

[HTML][HTML] Subtype-specific KRAS mutations in advanced lung adenocarcinoma: a retrospective study of patients treated with platinum-based chemotherapy

M Cserepes, G Ostoros, Z Lohinai, E Raso… - European journal of …, 2014 - Elsevier
… -specific KRAS mutational status in terms … KRAS mutations in this setting, we analysed the
so far largest cohort of Caucasian patients with KRAS mutant stage III-IV lung adenocarcinoma

Integrative analysis reveals distinct subtypes with therapeutic implications in KRAS-mutant lung adenocarcinoma

KE Liu, J Guo, K Liu, P Fan, Y Zeng, C Xu, J Zhong… - …, 2018 - thelancet.com
adenocarcinomas into three subtypes and found that HSP90 inhibitors selectively killed
KRAS and STK11 co-mutant … the heterogeneity of KRAS-mutant lung adenocarcinoma may be …

[HTML][HTML] Validation of the IASLC/ATS/ERS lung adenocarcinoma classification for prognosis and association with EGFR and KRAS gene mutations: analysis of 440 …

A Yoshizawa, S Sumiyoshi, M Sonobe… - Journal of Thoracic …, 2013 - Elsevier
… In this study, the proposed IASLC/ATS/ERS histologic subtypes of lung adenocarcinomas
could predict the prognosis of a patient who underwent surgical resection, and the IASLC/ATS/…

[HTML][HTML] The clinical relevance of pathologic subtypes in metastatic lung adenocarcinoma

TD Clay, H Do, V Sundararajan, MM Moore… - Journal of thoracic …, 2014 - Elsevier
subtyping adenocarcinoma in biopsy specimens from metastatic sites in patients with metastatic
lung adenocarcinoma… association of KRAS mutations and EGFR mutations with smoking …