… The activated microglial cells express various cytokines and growth factors in response to
neural … It is believed that activated microglia exert cytotoxic effects in the brain through two very …

… We demonstrated that the release of cytokines and NO showed different time courses after
stimulation by LPS. First, tumor necrosis factor (TNF) a was released with 1-h lag time, second …

… , microglial activation can promote Aβ clearance via microglia… The persistent microglial
activation stimulated by Aβ via the … microglial activation can relieve the inflammatory cytokines …

… In conclusion, we observed that brain-derived inflammatory cytokines and chemokines are
involved in symptoms emergence in ALF, independent of microglial activation. Furthermore …

… that microglial behavior is highly dependent on the (cytokine) … In principle, microglial
activation aims at CNS protection. … microglial activation will remain—and so the cytokine release. …

… As an endogenous ligand for the CD45 receptor, CD22 can reduce pro-inflammatory cytokine
TNFα production to inhibit microglial activation by combining with the CD45 receptor on …

… However, microglial immune functions are induced in areas of infection or injury. To
understand regulation of cytokines that are secreted by and act upon microglia, we examined …

… Microglial activation increase cytokine and secondary messenger release that lead to
transient physiological and behavioural responses that are beneficial to the host organism (top …

… Taken together, recent findings suggest that microglial activation and pro-inflammatory
cytokines merit interest as targets in the treatment of neurodegenerative disorders. …

… involves switching macrophage functional activation to include reduction of … cytokines,
and production of cytoactive factors involved in repair and reconstruction of the damaged brain. …