… The first mouse microphthalmia transcription factor (Mitf ) mutation was discovered over 60 …
oop-helix zipper (bHLH-Zip) transcription factors. Like Myc, Mitf regulates gene expression by …

… The Microphthalmia transcription factor plays a crucial role in melanocyte development;
mice lacking a functional microphthalmia gene product are devoid of all pigment cells. As a first …

… Microphthalmia-associated transcription factor (MITF) was initially shown to play a key
role in melanocyte differentiation through the direct transcriptional control of TYROSINASE, …

… Microphthalmia-associated transcription factor (MITF) … pigment cell-specific transcription of
the melanogenesis enzyme … is upregulated by other transcription factors, PAX3, SOX10, and …

Purpose. The protein encoded by the Microphthalmia gene (MITF) is a transcription factor
essential for the development and survival of melanocytes. It serves as a master regulator in …

The microphthalmia (mi) gene appears essential for pigment cell development and/or
survival, based on its mutation in mi mice. It has also been linked to the human disorder …

… of the lymphoid-enhancing factor-1 (LEF-1)/TCF transcription factors, containing a high-mobility-group
domain (27, 28). Thus, the LEF-1/TCF transcription factors mediate a nuclear …

… mediator of the lymphoid‐enhancing factor 1 (LEF‐1)/T‐cell factors (TCFs) family. Here we
… and leucine‐zipper region of microphthalmia‐associated transcription factor (MITF) and LEF…

… of the microphthalmia-associated transcription factor (Mitf). This transcription factor plays a
… Here we show that Mitf can redirect β-catenin transcriptional activity away from canonical …

The microphthalmia (MiT) subfamily of transcription factors includes TFE3, TFEB, TFEC, and
MITF. In the 2016 World Health Organization classification, MiT family translocation renal …