The protein encoded by the microphthalmia (mi) gene is a transcription factor essential for
the development and survival of melanocytes. Using a monoclonal antibody generated
against human Mi transcription factor protein (Mitf) the authors previously demonstrated that
Mitf expression is conserved in primary and metastatic malignant melanomas, and appears
to be a highly sensitive and specific melanocytic marker. Mitf expression in various
cutaneous nevi and cutaneous nonmelanocytic tumors has not been documented …