… histiocytomas, and 20 malignant peripheral nerve sheath tumors. … Microphthalmia
transcription factor may be a valuable addition to the marker panel used in diagnosing melanoma…

… in Dct regulation using cotransfections into B16 mouse melanoma cells. The Dct promoter
contains numerous binding sites for the Sox10 transcription factor, and Mitf and Sox10 act in a …

… Microphthalmia-associated transcription factor … malignant melanoma, being expressed in
all nevi studied and between 88% and 100% of primary and metastatic epithelioid melanoma ( …

… Malignant melanomas do not uniformly retain expression of … Microphthalmia transcription
factor (Mitf) is a melanocytic … as a histopathological marker for melanoma, Mitf expression was …

… work showed that microphthalmia transcription factor is a sensitive and specific melanocyte
marker for melanoma diagnosis ( 1 ) in the context of epithelioid melanoma and its limited …

… Malignant melanoma is an aggressive cancer known for its notorious resistance to most
current therapies. The basic helix-loop-helix microphthalmia transcription factor (… of melanoma. …

… by the microphthalmia (mi) gene is a transcription factor … generated against human Mi
transcription factor protein (Mitf) … in primary and metastatic malignant melanomas, and appears to …

… transcription factors specify discrete cell types. In melanocytes, MITF (microphthalmia-associated
transcription factor) has a dominant role that has been termed ‘master transcriptional …

… in all of the melanoma cell lines. In conclusion, our results strongly indicate that proteins of
the MITF transcription factor family are widely expressed in malignant cells of the melanocytic …

… Microphthalmia transcription factor (Mitf) is a nuclear transcription factor critical for the …
has been shown as a sensitive and specific marker for melanoma in histologic specimens. …