Microphthalmia transcription factor: a sensitive and specific melanocyte marker for melanoma diagnosis

R King, KN Weilbaecher, G McGill, E Cooley… - The American journal of …, 1999 - Elsevier
melanocytic gene products—an observation associated with diagnostic dilemmas. Microphthalmia
transcription factor (Mitf) is a melanocytic … postnatal viability of melanocytes. It serves …

Melanocytes and the Microphthalmia Transcription Factor Network

E Steingrímsson, NG Copeland, NA Jenkins - Annu. Rev. Genet., 2004 - annualreviews.org
… The first mouse microphthalmia transcription factor (Mitf ) … zipper (bHLH-Zip) transcription
factors. Like Myc, Mitf regulates … biology of melanocytes and helped to explain how melanocyte-…

Microphthalmia transcription factor in the immunohistochemical diagnosis of metastatic melanoma: comparison with four other melanoma markers

M Miettinen, M Fernandez, K Franssila… - The American journal …, 2001 - journals.lww.com
Microphthalmia transcription factor may be a valuable addition to the marker panel used in
diagnosing melanomaMicrophthalmia transcription factor (MITF) is a transcriptional regulator …

Diagnostic utility of microphthalmia transcription factor in malignant melanoma and other tumors

KL Chang, AL Folpe - Advances in anatomic pathology, 2001 - journals.lww.com
… or spindled forms of melanoma. Microphthalmia-associated transcription factor (MiTF) is
the most recently described and the only nuclear melanocytic marker. This article reviews the …

Microphthalmia transcription factor expression in cutaneous benign, malignant melanocytic, and nonmelanocytic tumors

R King, PB Googe, KN Weilbaecher… - The American journal …, 2001 - journals.lww.com
microphthalmia (mi) gene is a transcription factor essential for the development and survival
of melanocytes… antibody generated against human Mi transcription factor protein (Mitf) the …

… in response to oxidative stress: transient downregulation of melanocyte differentiation markers and possible involvement of microphthalmia transcription factor

C Jiménez-Cervantes… - Journal of cell …, 2001 - journals.biologists.com
melanocyte differentiation markers mRNAs was preceded by a decrease in microphthalmia
transcription factormicrophthalmia-dependent downregulation of the melanogenic enzymes. …

The melanocyte-specific isoform of the microphthalmia transcription factor affects the phenotype of human melanoma

E Selzer, V Wacheck, T Lucas, E Heere-Ress, M Wu… - Cancer research, 2002 - AACR
microphthalmia transcription factor MITF plays a pivotal role in the development and
differentiation of melanocytes. … as a marker capable of identifying subgroups of melanoma patients …

Role for microphthalmia transcription factor in the diagnosis of metastatic malignant melanoma

SR Granter, KN Weilbaecher, C Quigley… - Applied …, 2002 - journals.lww.com
… work showed that microphthalmia transcription factor is a sensitive and specific melanocyte
marker for melanoma diagnosis ( 1 ) in the context of epithelioid melanoma and its limited …

[PDF][PDF] Microphthalmia transcription factor: a specific marker for malignant melanoma

J Vachtenheim, J Borovansky - Prague Med Rep, 2004 - fyziologie.lf1.cuni.cz
… utility of microphthalmia transcription factor in malignant melanoma and … Microphthalmia
transcription factor in the … melanoma: comparison with four other melanoma markers. Am. J. …

Role of microphthalmia transcription factor in regulation of melanocyte differentiation marker TRP-1

D Fang, V Setaluri - Biochemical and biophysical research communications, 1999 - Elsevier
… In this study we investigated the role of the melanocyte-specific transcription factor MITF in
expression of TRP-1 in human melanoma cells. In the presence of the pharmacological agent …