… melanocytic differentiation in poorly differentiated or spindled forms of melanoma.
Microphthalmia-associated transcription factor (… and the only nuclear melanocytic marker. This …

… The first mouse microphthalmia transcription factor (Mitf ) … zipper (bHLH-Zip) transcription
factors. Like Myc, Mitf regulates gene … and sufficient determinant of melanocyte differentiation. …

… (MITF) is a key transcription factor for melanocyte development and differentiation. MITF
regulates expression of numerous pigmentation genes to promote melanocyte differentiation, as …

… In this study we investigated the role of the melanocyte-specific transcription factor MITF in
expression of TRP-1 in human melanoma cells. In the presence of the pharmacological agent …

… nevi with prominent Schwannian differentiation demonstrated decreased staining, and there
… prominent schwannian differentiation were negative for melanocytic differentiation marker …

… was specific for melanocytic differentiation because it was not … by the microphthalmia (mi)
gene, Mitf, is a transcription factor … of melanocytes and is important in regulating the melanocyte …

… Microphthalmia-associated transcription factor (MITF) was initially shown to play a key
role in melanocyte differentiation through the direct transcriptional control of TYROSINASE, …

… and survival of melanocytes as well as a key transcription factor regulating the expression of
… in melanocyte survival, we hypothesize that it is also involved in melanoma differentiation. …

… melanocytic gene products—an observation associated with diagnostic dilemmas. Microphthalmia
transcription factor (Mitf) is a melanocytic … postnatal viability of melanocytes. It serves …

… To further investigate the molecular basis of melanocyte differentiation induced by ATRA, …
treatment with ATRA, suggesting that this transcription factor may be the key molecule in this …