… synthesis or melanosome biogenesis. Here we show that a common transcriptional control
… albinism, as Oa1's function affects melanosome biogenesis. We demonstrated that Oa1 is a …

… (2003), which demonstrated that SILV and MLANA are direct transcriptional targets of MITF.
This report links for the first time MITF to melanosome biogenesis. Two E-box sequences, …

… Melanosomes are lysosome-related organelles specialized in melanin synthesis and … we
show that microphthalmia-associated transcription factor (MITF) silencing induces melanosome …

… promoter region with the gene encoding the melanosomal factor silver/gp100. In this manner…
of oxidative phosphorylation genes and mitochondrial biogenesis, thought to be caused by …

… by excessive exposure to UV radiation which triggers inappropriate biogenesis of melanin4.
… of reactions catalyzed by melanogenic enzymes in melanosome melanocytes. The activity …

Microphthalmia-associated transcription factor (MITF) acts via pigment epithelium-derived
factor (PEDF), an antiangiogenic protein, to regulate retinal pigment epithelium migration. …

… , melanosome biogenesis, and eye development [21]. Interestingly, studies have found
that TFEB and its ortholog HLH-30 in Caenorhabditis elegans are essential for diet-induced …

… In particular, many genes implicated in melanosome biogenesis have been characterized,
so that melanosomes represent an incredible source of … microphthalmia transcription factor …

… of the microphthalmia family of transcription factors (MiT), … melanosome biogenesis, and
melanosomes are frequently referred to as a lysosome-related organelle (LRO), melanosomes …

… on melanosome biogenesis, transport and transfer, melanogenic regulators in melanocytes,
and factors … that regulates melanocyte function is microphthalmia transcription factor (MITF), …