… ▪ Abstract The first mouse microphthalmia transcription factor (Mitf ) mutation was discovered
over 60 years ago, and since then over 24 spontaneous and induced mutations have been …

… Our data show that Mitf decreases cell proliferation and results in cells which grow in … Mitf
favored increased expression of tyrosinase and tyrosinase-related protein-1. In addition, Mitf …

… Microphthalmia-associated transcription factor (MITF) regulates the differentiation and … -specific
transcription of the melanogenesis enzyme genes. Hetero zygous mutations in the MITF …

… Microphthalmia-associated transcription factor (MiTF) is the most recently described … MiTF
and those published studies that have addressed its diagnostic sensitivity and specificity. MiTF …

… The basic helix-loop-helix microphthalmia transcription factor (MITF) is the master regulator
determining the identity and properties of the melanocyte lineage, and is regarded as a …

… -LZ) factor microphthalmia transcription factor (Mitf) plays a … More than 20 different Mitf
mutations have been described for … Mutations of the MITF gene in humans are associated with …

… Biochemical studies revealed that Microphthalmia transcription factor protein (Mitf) binds …
of Mitf followed by secondary Mitf-mediated activation of pigment enzyme expression. Mitf is not …

… Microphthalmia transcription factor (MITF) is one of the key regulators of melanocyte … to
activate transcription of genes required for melanogenesis in adult melanocytes (1–3). MITF is …

… One possibility is that Mitf recruits other key mediators to its target gene promoters. To
determine the potential of Mitf to interact with other transcription factors and coregulators we …

… Microphthalmia-associated transcription factor (MITF) was initially shown to play a key role in
melanocyte differentiation through the direct transcriptional … MITF, more than 40 direct MITF …