… Abstract: The transcription factor microphthalmia (MITF) is … , which are the downstream
transcriptional targets of MITF. It also … review is the possible utility of MITF as a marker of malignant …

… は,MITF遺伝子の発現制御機構を解明する目的で,MITF遺伝子をクロー ニングし,同遺伝子の転写
開始点を決定した.次いで,一時的発現系によりMITF… しかも,MITF自身による同遺伝 子の転写活性化が…

… Microphthalmia transcription factor (MITF) is a transcriptional … Microphthalmia transcription
factor has been shown to be … studies, melanocytes did not develop in MITF-deficient mice. …

… Microphthalmia-associated transcription factor (Mitf) is a … -LZ) family of transcription factors
[6], [7], [8]. Expression levels of … In view of Mitf as a transcription factor, we expected that Mitf …

… with microphthalmia-associated transcription factor (MITF) in melanoma cell lines and human
samples. High PEDF and MITF … criteria, whereas both factors are decreased in senescent …

… was regulated at the transcriptional level. Microphthalmia-associated transcription factor (MITF),
a … Furthermore, we show that MITF isoforms regulate transcription of PAI-1 differently, …

… Microphthalmia transcription factor (Mitf) is a nuclear transcription factor critical for the
development and survival of melanocytes and has been shown as a sensitive and specific marker …

… the melanocyte-specific transcription factor MITF in ex… MITF mRNA or immunoreactive MITF
protein. Expression of tyrosinase mRNA, on the other hand, correlated with the levels of MITF …

… In vitro and in vivoevidence suggest that microphthalmia transcription factor (MITF) plays
a key regulatory role in tissue-specific gene regulation in several cell types, including …

… We demonstrate that Mitf directly regulates Pax6 transcription … shown that microphthalmia
transcription factor (Mitf) expression is … Mitf, a basic-helix-loop-helix-leucine-zipper transcription …