… marrow-derived precursor cells blocked for p38 MAPK activity and the mi/mi … p38 MAPK in
osteoclasts. In this study, we investigate whether MITF is a potential target of the p38 MAPK in …

… Following a stress that causes a need for new cells to replenish BM and/or circulating
blood, the p38 MAPK pathway is activated in HSCs, with p38α promoting cell cycle entry and …

… of melanoma to current treatments using MAPK pathway targeting drugs, this review will
also address the role of MITF in melanoma development and BRAF/MEK inhibitor therapy. …

… pathway, the MAPK pathway, and the PI3K pathway. PAX3, SOX10, PGC1, LEF, and CREB
are some of the known transcription factors … by MAPK, ribosomal S6 kinase (RSK), and p38. C…

… of Wnt signaling, cAMP signaling may also affect Mitf function through the MAP kinase
pathway or the PI3K pathway (… Treatment of osteoclasts with Rankl results in p38 MAPK-mediated …

… of the PKC, MAPK, and cAMP pathways initiated by EDN receptor … Although MAPK is
known to link MITF to KIT signaling in … of the MAPK pathway. Here we demonstrate that EDN1 …

… signaling pathways to induce the transcription of genes necessary for osteoclast function is
the microphthalmia-associated transcription factor, … ) family transcription factor (Hodgkinson et …

… 2, p38, PI3 kinase and Akt, we show that the corresponding downstream signaling pathways
… by the activation of the Ras-Erk Map kinase pathway, treatment with a general Mek inhibitor, …

… of the transcription factor microphthalmia (MiTF) through the cooperative, unscheduled
activation of several stress-signaling pathways, including the SMAD2/3, p38 MAPK, NF-κB, and …

… 1), constitutively active Raf plus wild-type MEK were used to achieve sustained activation of
the MAPK pathway and permit measurable accumulation of luciferase. Co-transfection of Raf…