… -associated transcription factor (MITF) is required for terminal osteoclast differentiation and …
by colony stimulating factor (CSF)-1 and receptor-activator of nuclear factor-κB ligand (RANKL…

… by at least three transcription factors interacting with critical … Mac-1 signaling modulates
monocyte differentiation in vivo, … that Mac-1 signaling modulates monocyte maturation in vivo. …

… that are modulated. b, Normalized RNA expression of selected TFs over the differentiation
… We filtered all experiments with no interactions at significance level P value < 10 −5 for ease …

… of co-factor interaction with SOX proteins. Firstly, we consider Wnt signalling and SOX
protein interactions, where SOX proteins utilise a wide range of mechanisms to modulate Wnt …

… Additional transcription factors modulate RA signaling and induction of differentiation in a …
RA increases expression of the transcription factor SMAD3; SMAD3 then interacts with the …

… terminal bHLH transcription factor region, a pair of transmembrane domains separated by a
short loop and a C-terminal regulatory domain that mediates protein–protein interactions that …

… the thyroid differentiation genes Tg, TPO, and DuOX2, and, in turn, we confirmed the interaction
of … osteoclast differentiation and survival through the modulation of NF-κB signaling (61). …

… Directly inhibiting or activating the function of a transcription factor requires specific …
interactions. The discovery or design of small molecules that specifically modulate these interactions …

… sets of transcription factors can interact with each other to modify the transcriptional output …
mammary development can interact at the level of their effector transcription factors, we have …

… cell differentiation towards these distinct lineages. We also discuss the interactions of key
transcription factors at … by cytokines modulate TCR-mediated signal transduction is less clear. …