… rhythmicity, it is intuitive that alterations in the endogenous machinery regulating circadian …
and mood disorders, and, finally, we discuss strategies for manipulating (disturbed) circadian …

… basis to depression, with emphasis on the role of circadian … to date between circadian
genes and mood disorders. These … to mood disorders, disease recurrence and the circadian …

… Conceptual basis for using peripheral cells in circadian clock phenotyping. In the healthy
state, peripheral and SCN phenotypes are similar. When the clock has been altered (eg, …

… Expanding on this, we will discuss more general mechanistic links within the framework
of fundamental circadian principles, forming a sound conceptual basis for implementing …

… , mood disorders are often accompanied by abnormalities in the organization of the circadian
… Studies on animal models suggest that the basic circadian clock mechanism, which runs in …

… significance for the role of circadian rhythms in mood disorders, or a consequence of altered
… of the circadian pacemaker and a homeostatic sleep process impacting on mood, energy, …

… , behavioural, and neurobiological links to mood syndromes. Here, we outline evidence for
… ‘circadian depression’. We propose that key clinical characteristics of circadian depression …

… Several studies have reported links between the circadian genes and the mood disorders.
For example, BD has been associated with TIM, Clock (311 T to C), and BMal1 (see Murray & …

… of circadian clock genes on brain function. In this chapter, I will present evidence for … circadian
basis of mood disorders and then discuss the involvement of clock genes in such disorders…

… Two other major examples are the relations between circadian rhythms and basic metabolism
and circadian rhythms and cognition. See Venkataraman et al. (47) for a review of recent …