Cellular circadian clocks in mood disorders

MJ McCarthy, DK Welsh - Journal of biological rhythms, 2012 - journals.sagepub.com
… non-SCN clocks could contribute directly to the pathophysiology of BD/MDD. We hypothesize
that circadian clock dysfunction in non-SCN clocks is a trait marker of mood disorders, …

Circadian genes, rhythms and the biology of mood disorders

CA McClung - Pharmacology & therapeutics, 2007 - Elsevier
… individual genes that make up the clock in mood regulation. As well, … mood regulation are
becoming apparent. In this review, the evidence linking circadian rhythms and mood disorders, …

The circadian basis of mood disorders: recent developments and treatment implications

P Monteleone, M Maj - European Neuropsychopharmacology, 2008 - Elsevier
… rhythmicity, it is intuitive that alterations in the endogenous machinery regulating circadian
and mood disorders, and, finally, we discuss strategies for manipulating (disturbed) circadian

The role of the circadian clock in animal models of mood disorders.

D Landgraf, MJ McCarthy, DK Welsh - Behavioral neuroscience, 2014 - psycnet.apa.org
circadian clock may alter processes not involved in circadian … detailed understanding of the
clock, and good experimental … whether circadian clock dysfunction causes mood disorders

Chronobiology and mood disorders

A Wirz-Justice - Dialogues in clinical neuroscience, 2003 - Taylor & Francis
… Whether these disturbances are of etiological significance for the role of circadian rhythms
in mood disorders, or a consequence of altered behavior can only be dissected out with …

Prospects for circadian treatment of mood disorders

A Hühne, DK Welsh, D Landgraf - Annals of medicine, 2018 - Taylor & Francis
… by which circadian disruption leads to mood disorders are … clocks may contribute to the
development of mood disorders: (… , (2) internal desynchronization among body clocks, (3) low …

Circadian neurogenetics of mood disorders

J Mendoza, G Vanotti - Cell and tissue research, 2019 - Springer
… of mood-related disorders. Furthermore… clocks, beyond the SCN, in the circadian control of
mood. The comprehension of the circadian neural and genetic mechanisms underlying mood

Disruption of the circadian timing systems: molecular mechanisms in mood disorders

J Mendlewicz - CNS drugs, 2009 - Springer
… between circadian genes and mood disorders. These data demonstrate that … clock genes
have been implicated in susceptibility to mood disorders, disease recurrence and the circadian

Circadian rhythms in mood disorders

MR Scott, CA McClung - Circadian clock in brain health and disease, 2021 - Springer
… Altered behavioral rhythms are a fundamental diagnostic feature of mood disorders. … a
role for circadian rhythm disruptions in mood disorder pathophysiology. Molecular clock gene …

Biological rhythm disturbances in mood disorders

A Wirz-Justice - International clinical psychopharmacology, 2006 - journals.lww.com
… rhythm disturbances as characteristic of mood disorders. The present flourishing of circadian
biology has revealed the molecular basis of 24-h rhythmicity driven by ‘clock’ genes, as …