… Genetic disruption of Dnmt1 in mouse ESCs (mESCs) results in global loss of methylation
[… DNA methylation through cell division (Figure 2B). DNMT1 also has de novo methylation …

… of DNA methylation as an epigenetic barrier to reprogramming. (a) Human fibroblasts can
be fused with mouse … hand, this reprogramming cannot occur when the mouse putative DNA …

… In this study, we have provided the first complete description of the cycle of methylation
reprogramming in mouse preimplantation embryos. This cycle is initiated shortly after sperm …

… Genome-wide DNA methylation reprogramming occurs in mouse primordial germ cells (PGCs)
and preimplantation embryos, but the precise dynamics and biological outcomes are …

… In addition, loss of UHRF1 protein is also observed during the reprogramming of mouse
embryonic fibroblasts to induced pluripotent stem cells (iPSCs), causing a transient phase of …

… In order to understand the dynamics of methylation reprogramming on a large scale we have
carried out a comprehensive genome-wide analysis of promoter methylation in the mouse …

… that DNA methylation is not the inherited epigenetic mark, at least in the mouse model
used … We have found that DNA methylation at the A vy allele is not reprogrammed during …

… the early events of DNA methylation reprogramming in human and mouse PGCLCs. This
approach has also allowed us to characterize the DNA methylation changes during the initial …

… absence of DNA methylation leads to … DNA methylation from parental gametes, suggesting
that escape of post-fertilization DNA methylation reprogramming is prevalent in the mouse …

… study the comprehensive picture of the dynamic DNA methylation reprogramming that occurs
during PGC specification and its relationship with the histone modification reprogramming. …