DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
… DNA methylation patterns are highly dynamic between week 9 (W9) and W22 of gestation.
We investigate the impact of reprogramming on organ-specific DNA methylation … that mouse …
We investigate the impact of reprogramming on organ-specific DNA methylation … that mouse …
Dynamic reprogramming of histone acetylation and methylation in the first cell cycle of cloned mouse embryos
F Wang, Z Kou, Y Zhang, S Gao - Biology of reproduction, 2007 - academic.oup.com
… methylated and undergoes passive DNA demethylation following embryo development [3,
7]. However, the mechanism of this asymmetric reprogramming of DNA methylation in … DNA …
7]. However, the mechanism of this asymmetric reprogramming of DNA methylation in … DNA …
Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos
W Dean, F Santos, M Stojkovic… - Proceedings of the …, 2001 - National Acad Sciences
… A similar reprogramming cycle occurs in mouse … some DNA sequences were more highly
methylated in cloned versus normal morulae. Here we show that methylation reprogramming is …
methylated in cloned versus normal morulae. Here we show that methylation reprogramming is …
DNA methylation and hydroxymethylation in stem cells
… If the loss of DNA methylation at pluripotent genes is not achieved, cells will be only …
reprogrammed.23 Low-passage mouse and human iPSCs harbour residual DNA methylation ‘…
reprogrammed.23 Low-passage mouse and human iPSCs harbour residual DNA methylation ‘…
Programming and inheritance of parental DNA methylomes in mammals
… Additionally, very little is known about the DNA methylation … current knowledge on methylation
reprogramming in mammals … mice, and identified about 4.4 million SNPs. We collected …
reprogramming in mammals … mice, and identified about 4.4 million SNPs. We collected …
DNA methylation programming and reprogramming in primate embryonic stem cells
NM Cohen, V Dighe, G Landan, S Reynisdottir… - Genome …, 2009 - genome.cshlp.org
DNA methylation is an important epigenetic mechanism, affecting normal development and …
reprogramming epigenomes during stem cell derivation. Here we report on DNA methylation …
reprogramming epigenomes during stem cell derivation. Here we report on DNA methylation …
[HTML][HTML] DNA demethylation, Tet proteins and 5-hydroxymethylcytosine in epigenetic reprogramming: an emerging complex story
… of reprogramming events, and understanding DNA methylation … potential drivers of epigenetic
reprogramming. Although some of … Moreover, Tet1 KO and Tet1/2 DKO mice have a fertility …
reprogramming. Although some of … Moreover, Tet1 KO and Tet1/2 DKO mice have a fertility …
DNA methylation dynamics of the human preimplantation embryo
… may regulate global versus targeted reprogramming 15 . … with a methylation difference >0.1
between mouse ICM and mouse … mouse ICM if its methylation level is more similar to mouse …
between mouse ICM and mouse … mouse ICM if its methylation level is more similar to mouse …
[HTML][HTML] Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice
Y Seki, K Hayashi, K Itoh, M Mizugaki, M Saitou… - Developmental …, 2005 - Elsevier
… within mouse centromeres and the SINES. To analyze genome-wide DNA methylation changes
… 2Aa,e), indicating that the genome-wide DNA methylation level is comparable between …
… 2Aa,e), indicating that the genome-wide DNA methylation level is comparable between …
Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors
AC Planello, J Ji, V Sharma, R Singhania, F Mbabaali… - Cell regeneration, 2014 - Springer
… (a DNA methylation inhibitor) increase reprogramming efficiency suggesting that the resistance
of somatic cell chromatin to remodeling is a barrier to reprogramming [… by reprogramming …
of somatic cell chromatin to remodeling is a barrier to reprogramming [… by reprogramming …