Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation
UM Munoz-Najar, KM Neurath, F Vumbaca, KP Claffey - Oncogene, 2006 - nature.com
… MT1-MMP-expressing breast cancer cell lines through a BM barrier was dramatically increased
by hypoxia. Experiments using MMP … activated MT1-MMP and required pro-MMP-2. pro-…
by hypoxia. Experiments using MMP … activated MT1-MMP and required pro-MMP-2. pro-…
[HTML][HTML] Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells
MA Cepeda, JJH Pelling, CL Evered, KC Williams… - Molecular cancer, 2016 - Springer
… Additionally, we analyzed the level of MT1-MMP protein in human 21 T breast cancer cell …
mammary carcinoma (IMC), to show that the metastatic cell line produces little MT1-MMP …
mammary carcinoma (IMC), to show that the metastatic cell line produces little MT1-MMP …
MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells
H Pulyaeva, J Bueno, M Polette, P Birembaut… - Clinical & experimental …, 1997 - Springer
… We further investigated the presence of the MT1MMP mRNA transcript in Con A treated and
untreated HBC cell lines with differential MMP-2 activation potentials. Northern analyses for …
untreated HBC cell lines with differential MMP-2 activation potentials. Northern analyses for …
Cancer cell–associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors
JY Perentes, ND Kirkpatrick, S Nagano, EY Smith… - Cancer research, 2011 - AACR
… in mammary tumors. Our findings show that cancer cell MT1-MMP expression promotes
cancer cell … We also show that cancer cell MT1-MMP expression correlates with BVI in human …
cancer cell … We also show that cancer cell MT1-MMP expression correlates with BVI in human …
Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells
… MT1MMP in both stromal and breast cancer cells. This further indicates that activation of MMP2
by MT1-MMP … stromal made MT1-MMP and by MT1-MMP expressed by cancer cells, both …
by MT1-MMP … stromal made MT1-MMP and by MT1-MMP expressed by cancer cells, both …
[HTML][HTML] MT1-MMP in breast cancer: induction of VEGF-C correlates with metastasis and poor prognosis
G Yao, P He, L Chen, X Hu, F Gu, C Ye - Cancer Cell International, 2013 - Springer
… -MMP levels in five breast carcinoma cell lines and correlated these levels with the invasive
activity of breast cancer cells. … -C and MT1-MMP expression and compared these results with …
activity of breast cancer cells. … -C and MT1-MMP expression and compared these results with …
[HTML][HTML] Monitoring and inhibiting MT1-MMP during cancer initiation and progression
S Pahwa, MJ Stawikowski, GB Fields - Cancers, 2014 - mdpi.com
… The probe was validated in C6 glioma cells and MCF-7 breast cancer cells as MT1-MMP …
of anti-MT1-MMP mAb-ROX bound to MT1-MMP was measured and compared to cells treated …
of anti-MT1-MMP mAb-ROX bound to MT1-MMP was measured and compared to cells treated …
Control of MT1-MMP transport by atypical PKC during breast-cancer progression
C Rossé, C Lodillinsky, L Fuhrmann… - Proceedings of the …, 2014 - National Acad Sciences
… and matrix remodeling by tumor cells by regulating endosome-to-… 1-matrix metalloproteinase
(MT1-MMP) in breast-cancer cells. Further analysis shows that atypical PKCι and MT1-MMP …
(MT1-MMP) in breast-cancer cells. Further analysis shows that atypical PKCι and MT1-MMP …
Clinical significance of MT1-MMP mRNA expression in breast cancer
K Mimori, H Ueo, C Shirasaka… - Oncology …, 2001 - spandidos-publications.com
… The localization of MTl-MMP has not been determined yet. Therefore, the purpose of this …
MTl-MMP in breast cancer by the measurement of mRNA expressions of MTl-MMP objectively. …
MTl-MMP in breast cancer by the measurement of mRNA expressions of MTl-MMP objectively. …
Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue
MA Mohammad, AA Zeeneldin… - Molecular and cellular …, 2012 - Springer
… that could induce the expression of MMP-2 in human tumors. In vitro studies have shown
that … of colon cancer cells through the induction of MT1-MMP, which activates pro-MMP-2. …
that … of colon cancer cells through the induction of MT1-MMP, which activates pro-MMP-2. …
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