Nuclear hormone receptors and gene expression

A Aranda, A Pascual - Physiological reviews, 2001 - journals.physiology.org
… The goal of this work is to review the progress in the field of transcriptional regulation by
nuclear receptors. We start by describing the domain structure of nuclear receptors and the …

[HTML][HTML] Nuclear receptor expression links the circadian clock to metabolism

X Yang, M Downes, TY Ruth, AL Bookout, W He… - Cell, 2006 - cell.com
… To study the temporal relationship between nuclear receptor expression and metabolic
processes, we compiled a dynamic atlas of the NR expression in four key metabolic tissues (liver, …

[HTML][HTML] Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

AL Bookout, Y Jeong, M Downes, TY Ruth, RM Evans… - Cell, 2006 - cell.com
… can be obtained not only by studying the expression of individual receptors but also by
studying expression of the nuclear receptor superfamily as a whole using a systems biology …

Nuclear receptor structure: implications for function

DL Bain, AF Heneghan… - Annu. Rev …, 2007 - annualreviews.org
nuclear receptor proteins, ligand-activated transcription factors capable of regulating the
expression … This review addresses the structure and structural properties of nuclear receptors, …

Nuclear receptors in human immune cells: expression and correlations

AB Schote, JD Turner, J Schiltz, CP Muller - Molecular immunology, 2007 - Elsevier
… in expression between individual nuclear receptor pairs in the … Distinct correlation patterns
were observed between receptor … , the relative expression level of a number of receptor pairs …

[HTML][HTML] Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression

S Bertrand, B Thisse, R Tavares, L Sachs… - PLoS …, 2007 - journals.plos.org
Nuclear receptors (NRs) are transcription factors that are implicated in several biological
processes such as embryonic development, homeostasis, and metabolic diseases. To study the …

[HTML][HTML] Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli

L Pei, A Castrillo, M Chen, A Hoffmann… - Journal of biological …, 2005 - ASBMB
… and liver X receptor in the control of lipid-dependent gene expression and inflammation. …
expression of a third group of nuclear receptors, the NR4A ligand-independent orphan receptors

Transcription in four dimensions: nuclear receptor‐directed initiation of gene expression

R Métivier, G Reid, F Gannon - EMBO reports, 2006 - embopress.org
nuclear receptor (NR)‐driven gene expression as a model system. NRs are a subfamily of
transcription factors, and include ligand‐dependent transcription factors, such as receptors for …

Nuclear receptor expression in fetal and pediatric liver: correlation with CYP3A expression

CA Vyhlidal, R Gaedigk, JS Leeder - Drug metabolism and disposition, 2006 - ASPET
… , nuclear receptor mRNA expression demonstrates considerable interindividual variability
in human fetal and pediatric liver and is significantly correlated with CYP3A expression. …

Tissue-specific mRNA expression profiles of human nuclear receptor subfamilies

M Nishimura, S Naito, T Yokoi - Drug metabolism and pharmacokinetics, 2004 - Elsevier
… The mRNA expression of 33 nuclear receptors (NR1A1, 1A2, 1B1, 1B2, 1B3, 1C1, 1C2, 1C3…
of the mRNA expression of 43 human nuclear receptors. The mRNA expression profiles of …