[HTML][HTML] Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

SI Mota, RO Costa, IL Ferreira, I Santana… - … Basis of Disease, 2015 - Elsevier
… Evidence of early oxidative stress defense mechanisms in AD … stress was also detected in
the brain cortex of young female and old male 3xTg-AD mice. We demonstrate oxidative stress

Copper and oxidative stress in the pathogenesis of Alzheimer's disease

G Eskici, PH Axelsen - Biochemistry, 2012 - ACS Publications
… the relationships among copper, oxidative stress, and Alzheimer’s disease with the aim of
… by which copper dysregulation may be linked to AD pathogenesis through oxidative stress. …

Oxidative stress: a bridge between Down's syndrome and Alzheimer's disease

M Zana, Z Janka, J Kálmán - Neurobiology of aging, 2007 - Elsevier
… analogies between Down's syndrome (DS) and Alzheimer's disease (AD), there is ample
evidence of the involvement of oxidative stress (OS) in the pathogenesis of both disorders. The …

Methionine‐35 of Aβ(1–42): Importance for Oxidative Stress in Alzheimer Disease

DA Butterfield, R Sultana - Journal of amino acids, 2011 - Wiley Online Library
… Consistent with the role of Aβ in oxidative stress induction and consequently in AD
pathogenesis, our laboratory and others showed that Aβ-induced oxidative stress markers can be …

Reactive oxygen species mediate cellular damage in Alzheimer disease

G Perry, RJ Castellani, K Hirai… - … of Alzheimer's Disease, 1998 - content.iospress.com
… Therefore, we contend that oxidative stress is the element that links the multitude of … summary,
oxidative stress may underline all of the commonly accepted notions in Alzheimer disease

Oxidative stress and redox‐active iron in Alzheimer's disease

K Honda, G Casadesus, RB Petersen… - Annals of the new …, 2004 - Wiley Online Library
… indicate that oxidative stress is one of the earliest events in the genesis of Alzheimer's disease
(… In this review, we consider the role of iron-induced oxidative stress as a key event in AD …

Amyloid β-protein toxicity and oxidative stress in Alzheimer's disease

C Behl - Cell and tissue research, 1997 - Springer
… This review focuses on the oxidative-stress hypothesis of AD and on novel antioxidative …
induction of oxidative stress by Ab in neurons, and potential sources of oxidative events in …

The heat shock/oxidative stress connection: relevance to Alzheimer disease

MA Pappolla, M Sos, RA Omar… - Molecular and chemical …, 1996 - Springer
… This study provided morphologic evidence in support of a role for oxidative stress in AD,
because it showed that markers of oxidation are colocalized with the neuropathologic lesions. …

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

G Perry, PI Moreira, MS Santos… - CNS & Neurological …, 2008 - ingentaconnect.com
oxidative stress in Alzheimer disease. Furthermore, it has been suggested that in the initial
stages of the development of Alzheimer disease, … we provide evidence that oxidative stress is …

Air Pollution, Oxidative Stress, and Alzheimer′ s Disease

PV Moulton, W Yang - Journal of environmental and public …, 2012 - Wiley Online Library
… —and AD via oxidative stress is the … oxidative stress [17]. When ROS formation exceeds the
capacity of the antioxidant defense systems oxidative stress occurs, which results in oxidative