A glance of p53 functions in brain development, neural stem cells, and brain cancer
Y Xiong, Y Zhang, S Xiong, AE Williams-Villalobo - Biology, 2020 - mdpi.com
… role of p53 in brain development, neural stem cell regulation and the mechanisms of inactivating
p53 … p53′s functions in brain development and neural stem cell regulation, as well as …
p53 … p53′s functions in brain development and neural stem cell regulation, as well as …
Novel perspectives on p53 function in neural stem cells and brain tumors
SM Hede, I Nazarenko, M Nistér… - Journal of …, 2011 - Wiley Online Library
… tumor stem cells, … p53 in brain tumors and neural stem cells. Specifically, we review the
literature regarding transformation of adult neural stem cells and, we discuss how the loss of p53 …
literature regarding transformation of adult neural stem cells and, we discuss how the loss of p53 …
p53 suppresses the self-renewal of adult neural stem cells
… the function of p53 in neural stem cells in the adult brain, and report that it acts as a negative
regulator of neural stem cell … To assess a potential role for p53 in the adult neural stem cell …
regulator of neural stem cell … To assess a potential role for p53 in the adult neural stem cell …
Hedgehog controls neural stem cells through p53‐independent regulation of Nanog
… Consistent with the notion that Nanog may confer stemness features to somatic cells, we also
show that Nanog is upregulated in Hh‐promoted neuronal tumors, specifically featuring the …
show that Nanog is upregulated in Hh‐promoted neuronal tumors, specifically featuring the …
p53 regulates the self-renewal and differentiation of neural precursors
A Armesilla-Díaz, P Bragado, I Del Valle, E Cuevas… - Neuroscience, 2009 - Elsevier
… the role of p53 in OB neural progenitor cells by comparing neurosphere cultures obtained
from p53 knockout (p53KO) and p53 wild … We observed that lack of p53 promotes neurosphere …
from p53 knockout (p53KO) and p53 wild … We observed that lack of p53 promotes neurosphere …
p53 regulates neural stem cell proliferation and differentiation via BMP-Smad1 signaling and Id1
… Neural stem cells (NSCs) play essential roles in nervous … Here we present evidence that
tumor suppressor p53 regulates NSC … p53 deficiency led to increased neurogenesis in vivo, and …
tumor suppressor p53 regulates NSC … p53 deficiency led to increased neurogenesis in vivo, and …
Cross talk between cellular redox status, metabolism, and p53 in neural stem cell biology
K Forsberg, S Di Giovanni - The Neuroscientist, 2014 - journals.sagepub.com
… in stem cell quiescence and fate commitment. Here, we explore the known and putative
functions of p53 … reactive oxygen species, p53, and related cellular signaling may regulate NSC …
functions of p53 … reactive oxygen species, p53, and related cellular signaling may regulate NSC …
A GLI1‐p53 inhibitory loop controls neural stem cell and tumour cell numbers
B Stecca, A Ruiz i Altaba - The EMBO journal, 2009 - embopress.org
… We suggest a role for endogenous Gli1 in neural stem cells as enhanced GLI1 levels expand
the number of clonogenic stem cells, and Prominin1 + stem cells from DT +dox cerebella …
the number of clonogenic stem cells, and Prominin1 + stem cells from DT +dox cerebella …
p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids
A Marin Navarro, RJ Pronk, AT van der Geest… - Cell death & …, 2020 - nature.com
… neural stem cell function to in vitro cortical neurogenesis, we show that p53 aids in proper
neural stem cell … function. Taken together, our 2D and 3D models derived from human iPS …
neural stem cell … function. Taken together, our 2D and 3D models derived from human iPS …
p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation
… Mouse neural stem cells used in this study were obtained from Dr. Reynold's Laboratory
at the University of Queensland, Brisbane, Australia, and provided by Dr. Low's Laboratory at …
at the University of Queensland, Brisbane, Australia, and provided by Dr. Low's Laboratory at …
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