Beyond neurons: evidence that immune and glial cells contribute to pathological pain states
LR Watkins, SF Maier - Physiological reviews, 2002 - journals.physiology.org
… pain states in both humans and laboratory animals. Of the variety of substances released by
activated immune and glial cells… Although this review focuses on immune modulation of pain…
activated immune and glial cells… Although this review focuses on immune modulation of pain…
Immune and glial cell factors as pain mediators and modulators
SB McMahon, WBJ Cafferty, F Marchand - Experimental neurology, 2005 - Elsevier
… for many novel pain mediators. The old … cells—predominantly immune and glial cells. The
evidence is now growing apace that these are important mediators of persistent pain states …
evidence is now growing apace that these are important mediators of persistent pain states …
The neuro-immune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines
PJ Austin, G Moalem-Taylor - Journal of neuroimmunology, 2010 - Elsevier
… Activation of immune and immune-like glial cells in the injured … pain chronicity is established.
This review will critically examine the role of the immune system in modulating chronic pain …
This review will critically examine the role of the immune system in modulating chronic pain …
The role of glia and the immune system in the development and maintenance of neuropathic pain
… Glial cells, also known as neuroglia, are nonconducting cells that modulate neurotransmission
at the synaptic level. Glial cells can be … pain state, but rather potentiation of a pain state. …
at the synaptic level. Glial cells can be … pain state, but rather potentiation of a pain state. …
Nonneuronal central mechanisms of pain: glia and immune response
EA Romero-Sandoval, S Sweitzer - Progress in Molecular Biology and …, 2015 - Elsevier
… of glial cells in the context of pain. This chapter explores the available literature to objectively
ponder the potential role of glial cells in human pain … from acute to persistent pain states. …
ponder the potential role of glial cells in human pain … from acute to persistent pain states. …
The neuropathic pain triad: neurons, immune cells and glia
J Scholz, CJ Woolf - Nature neuroscience, 2007 - nature.com
… of common clinical pain states. In this review we focus on immune and glial cell responses
to … Recognition of the critical involvement of immune cells and glia in the pathophysiological …
to … Recognition of the critical involvement of immune cells and glia in the pathophysiological …
Spinal glial activation contributes to pathological pain states
H Cao, YQ Zhang - Neuroscience & Biobehavioral Reviews, 2008 - Elsevier
… In the spinal cord, microglia, oligodendrocytes and astrocytes form a large group of glial
cells. Microglia are the immune system's ambassadors to the CNS, closely related to …
cells. Microglia are the immune system's ambassadors to the CNS, closely related to …
[HTML][HTML] Opioid receptors in immune and glial cells—implications for pain control
H Machelska, MÖ Celik - Frontiers in immunology, 2020 - frontiersin.org
… immune cells and glia in the modulation of pain. All four opioid receptors have been identified
at the mRNA and protein levels in immune cells (… immune and glial cells to pain control. …
at the mRNA and protein levels in immune cells (… immune and glial cells to pain control. …
Do glial cells control pain?
… Thus, glial cells can powerfully control pain when they are activated to produce various pain
… cord is an important feature of glial activation because, in the resting state, very few glial …
… cord is an important feature of glial activation because, in the resting state, very few glial …
Pathophysiology of peripheral neuropathic pain: immune cells and molecules
MA Thacker, AK Clark, F Marchand… - Anesthesia & …, 2007 - journals.lww.com
… Schwann cells may contribute to some neuropathic pain states, … population of satellite glial
cells, as well as cells expressing … of T cells that perform an immune surveillance function as in …
cells, as well as cells expressing … of T cells that perform an immune surveillance function as in …
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