Effect of poly (amidoamine)(PAMAM) dendrimer on skin permeation of 5-fluorouracil

VVK Venuganti, OP Perumal - International Journal of Pharmaceutics, 2008 - Elsevier
… In the present study, dendrimer increased the water solubility of 5FU in PB from 17 to 30
mg/ml but this did not result in increased flux. It should be noted that 5FU concentration used for …

Poly (amidoamine)(PAMAM) dendritic nanostructures for controlled sitespecific delivery of acidic anti-inflammatory active ingredient

A Asthana, AS Chauhan, PV Diwan, NK Jain - Aaps Pharmscitech, 2005 - Springer
… and other rheumatic disorders. Parenteral dosage form of FB is not available in the market
because of its very low aqueous solubility. … In the present study, the PAMAM dendrimers were …

Impact of dendrimers on solubility of hydrophobic drug molecules

S Choudhary, L Gupta, S Rani, K Dave… - Frontiers in …, 2017 - frontiersin.org
… the effects pf PAMAM dendrimers on aqueous solubility of AmB. The results showed an
enhancement in solubility of AmB when in combination with PAMAM dendrimers (G1). AmB …

Solubility of nicotinic acid in polyamidoamine dendrimer solutions

C Yiyun, X Tongwen - European journal of medicinal chemistry, 2005 - Elsevier
… (PAMAM) dendrimers on the aqueous solubility of nicotinic acid. The aqueous solubility of
… measured in the presence of dendrimers at room temperature in distilled water. The effect of …

Evaluation of phenylbutazone and poly (amidoamine) dendrimers interactions by a combination of solubility, 2D-NOESY NMR, and isothermal titration calorimetry …

W Yang, Y Li, Y Cheng, Q Wu, L Wen, T Xu - Journal of pharmaceutical …, 2009 - Elsevier
PAMAM dendrimers than that in the case of G6 dendrimer. According to the aqueous solubility
results, 2 mg/mL G3 PAMAM dendrimer … than G6 PAMAM dendrimers at the same mass …

Dendrimer for solubility enhancement

B Gorain, M Pandey, H Choudhury, GK Jain… - Dendrimer-based …, 2021 - Elsevier
… Thus Luong and group had developed PAMAM dendrimer to improve the aqueous
solubility of another plant flavonoid, 3,4-difluorobenzylidene diferuloylmethane (CDF) [45]. …

[HTML][HTML] Starburst pamam dendrimers: Synthetic approaches, surface modifications, and biomedical applications

R Kharwade, S More, A Warokar, P Agrawal… - Arabian Journal of …, 2020 - Elsevier
… As compared to linear polymer, PAMAM dendrimer generally showed higher solubility and
… The solubility of PAMAM dendrimers is robustly dependent on various components such as …

PAMAM dendrimers as a carbamazepine delivery system for neurodegenerative diseases: A biophysical and nanotoxicological characterization

DE Igartúa, CS Martinez, CF Temprana… - International Journal of …, 2018 - Elsevier
… with PAMAM dendrimers increment their solubility in water … on PAMAM dendrimers for the
treatment of neurodegenerative disorders. This strategy is focused on increasing CBZ solubility

… interaction versus internal encapsulation between cationic dendrimers and negatively charged drugs: which contributes more to solubility enhancement of the drugs?

Y Cheng, Q Wu, Y Li, T Xu - The Journal of Physical Chemistry B, 2008 - ACS Publications
… We have demonstrated the relationships between electrostatic attachment and encapsulation
of negatively charged drugs to PAMAM dendrimers by aqueous solubility and NMR studies…

G5 PAMAM dendrimer versus liposome: A comparison study on the in vitro transepithelial transport and in vivo oral absorption of simvastatin

R Qi, H Zhang, L Xu, W Shen, C Chen, C Wang… - … , Biology and Medicine, 2015 - Elsevier
… This study compared formulation effects of a dendrimer and a liposome preparation on the
water solubility, transepithelial transport, and oral bioavailability of simvastatin (SMV). Amine-…