Synthesis of cationic water-soluble light-harvesting dendrimers

S Wang, JW Hong, GC Bazan - Organic letters, 2005 - ACS Publications
… We chose as synthetic targets four generations of PAMAM dendrimers with either …
amine groups on the terminal chromophores are protonated; the PAMAM interior is neutral. …

PAMAM dendrimers as nanoscale oral drug delivery systems

KM Kitchens, H Ghandehari - Nanotechnology in Drug Delivery, 2009 - Springer
… Molecular geometry and surface charge also influence the microvascular extravasation of
water-soluble polymers across the endothelial barrier, in which compact, spherical, positively …

Interaction between PAMAM-NH2 G4 dendrimer and paracetamol in aqueous solution

A Buczkowski, P Urbaniak, B Palecz - Journal of Molecular Liquids, 2013 - Elsevier
solubility in aqueous solutions of PAMAM-NH 2 G4 dendrimer confirm the paracetamol addition
to this dendrimer… paracetamol and dendrimer due to the low water-solubility of ibuprofen. …

PAMAM dendrimers—Diverse biomedical applications. Facts and unresolved questions

M Labieniec, C Watala - Central European Journal of Biology, 2009 - Springer
… desirable properties, affected the water solubility and reduced the hydrodynamic volume [41,42].
Partial conversion of cationic PAMAM dendrimers into lauroyl end groups increased …

[PDF][PDF] PAMAM Dendrimers mediated solubility enhancement of poorly soluble drugs: a concise review

SP Gautam, AK Gupta, SUD Wani, N Malviya… - Int. J. Pharm. Drug …, 2015 - researchgate.net
… , LJ, Wain, CF Dendrimers as potential drug carriers; encapsulation … water soluble PAMAM
dendrimers. Tetrahedron 2003;59:3873-80 . 14. Liu, M., Kono, K., Freche,t JM Water soluble

… glycol–polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in water

H Yang, JJ Morris, ST Lopina - Journal of colloid and interface science, 2004 - Elsevier
PAMAM dendrimer increases pyrene solubility from 6.44×10 −7 to 6.8×10 −7 M. A 8.8×10 −5
M dendrimer raised pyrene solubilitydendrimer, only yielded a 1.72-fold increase in pyrene …

Application of dendrimer–drug complexation in the enhancement of drug solubility and bioavailability

NK Jain, U Gupta - Expert opinion on drug metabolism & toxicology, 2008 - Taylor & Francis
water soluble PAMAM dendrimers. The acidic molecules were bound within the tertiary nitrogens
of the PAMAM dendrimers … In another study ∼ 40 ibuprofen molecules were loaded per …

Complexation of Mefenamic Acid by Low‐Generation PAMAM Dendrimers: Insight from NMR Spectroscopy Studies and Molecular Dynamics Simulations

PA Barra, L Barraza, VA Jiménez… - Macromolecular …, 2014 - Wiley Online Library
… anionic poorly soluble drug with low-generation PAMAM-G2 and PAMAM-G3 dendrimers
(… In this work, aqueous solubility studies are employed to determine the average complex …

Poly (amidoamine) dendrimers as a pharmaceutical excipient. Are we there yet?

DP Otto, MM De Villiers - Journal of pharmaceutical sciences, 2018 - Elsevier
… l-alanine, as water-soluble drugs, and phenylbutazone and primidone, as poorly water-soluble
drugs, were used in a computational simulation with G5 PAMAM dendrimers. At a neutral …

Structure–function relationship of PAMAM dendrimers as robust oil dispersants

NK Geitner, B Wang, RE Andorfer… - … science & technology, 2014 - ACS Publications
… , as PN water solubility increases exponentially with temperature over the observed range
(… between PAMAM dendrimers, using G4-NH 2 as our model, and different hydrocarbons. …