PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

F Abedi-Gaballu, G Dehghan, M Ghaffari, R Yekta… - Applied materials …, 2018 - Elsevier
… efficient nanosystems for drug delivery are increasingly being investigated. Polyamidoamine
(PAMAM) dendrimersPAMAM dendrimers with a high density of cationic charges display …

Activated and non-activated PAMAM dendrimers for gene delivery in vitro and in vivo

G Navarro, CT de ILarduya - Nanomedicine: Nanotechnology, Biology and …, 2009 - Elsevier
… G5 dendrimerDNA complexes are superior to the nonactivated ones in terms of gene transfer
… results showed that G4 and G5 PAMAM dendrimers are an effective nanosystem for gene

[HTML][HTML] Recent advances in preclinical research using PAMAM dendrimers for cancer gene therapy

P Tarach, A Janaszewska - International Journal of Molecular Sciences, 2021 - mdpi.com
… Poly(amidoamine) (PAMAM) dendrimers are repetitively … During the last 10 years of research
on PAMAM dendrimers, … development of PAMAM dendrimers in anticancer gene therapies, …

Facile formation of PAMAM dendrimer nanoclusters for enhanced gene delivery and cancer gene therapy

SL Mekuria, J Li, C Song, Y Gao, Z Ouyang… - ACS Applied Bio …, 2021 - ACS Publications
… superstructured dendrimeric nanosystems to overcome … PAMAM dendrimer-based NCs for
enhanced gene delivery applications. Through the judicious design, G3 PAMAM dendrimers

PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery

D Luong, P Kesharwani, R Deshmukh, MCIM Amin… - Acta biomaterialia, 2016 - Elsevier
drug delivery strategies, PEGylated PAMAM dendrimer is one of the most effective nano-carriers
to deliver … This study indicated that such PEGylated dendrimer based nanosystems

PAMAM dendrimer/pDNA functionalized-magnetic iron oxide nanoparticles for gene delivery

S Xiao, R Castro, J Rodrigues, X Shi… - Journal of biomedical …, 2015 - ingentaconnect.com
… Joining the advantages of PAMAM dendrimers and magnetic … iron oxide nanoparticles with
PAMAM dendrimer/pDNA using an … PAMAM dendrimer/pDNA-coated MNPs as gene delivery

Functionalized PAMAM constructed nanosystems for biomacromolecule delivery

KH Wong, Z Guo, MK Law, M Chen - Biomaterials Science, 2023 - pubs.rsc.org
… For example, transferrin was conjugated to a PAMAM dendrimer for gene delivery to cancer
cells. The transferrin not only targeted the transferrin receptors overexpressed in the tumor …

Dendrimer nanohybrid carrier systems: an expanding horizon for targeted drug and gene delivery

P Kesharwani, A Gothwal, AK Iyer, K Jain… - Drug discovery today, 2018 - Elsevier
… It is assumed that such emerging hybrid nanosystems – from combining two already-established
drug delivery platforms – could lead the way for the development of newer delivery

Surface functionalized dendrimers as controlled-release delivery nanosystems for tumor targeting

M Ghaffari, G Dehghan, F Abedi-Gaballu… - European Journal of …, 2018 - Elsevier
drug and gene delivery owing to multivalent and host-guest entrapment properties. However,
dendrimers … of dendrimer as a gene delivery vector in vivo and in vitro. Functionalization of …

Development of targeted gene delivery system based on liposome and PAMAM dendrimer functionalized with hyaluronic acid and TAT peptide: In vitro and in vivo …

M Ebrahimian, M Hashemi, M Farzadnia… - Biotechnology …, 2022 - Wiley Online Library
… efficient drug and gene delivery nanosystems is polyamidoamine (PAMAM) dendrimers with
… non-immunogenic which make them suitable for delivery of genetic materials. Surface of …