PAMAM dendrimers in drug delivery: Loading efficacy and polymer morphology
P Chanphai, L Bekale… - Canadian Journal of …, 2017 - cdnsciencepub.com
… Taken together, our data suggest that PAMAM dendrimers are capable of transporting
doxorubicin and tamoxifen in vitro. This demonstrates the importance of PAMAM dendrimers as a …
doxorubicin and tamoxifen in vitro. This demonstrates the importance of PAMAM dendrimers as a …
PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy
… The TMScu encapsulation efficacy and the drug loading rates were 77.8 ± 0.69% and 6.2
± 0.06%, respectively. Also, the highest percentage of TMScu release from the TMScu/…
± 0.06%, respectively. Also, the highest percentage of TMScu release from the TMScu/…
PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery
… PEGylated PAMAM dendrimers have a higher anticancer drugs loading with the sustained
and controlled drug release property for efficient tumor uptake [21], [22]. PEGylated …
and controlled drug release property for efficient tumor uptake [21], [22]. PEGylated …
Characterization of folic acid-PAMAM conjugates: drug loading efficacy and dendrimer morphology
P Chanphai, HA Tajmir-Riahi - Journal of Biomolecular Structure …, 2018 - Taylor & Francis
… We report the loading efficacy of folic acid (FA) by polyamidoamine (PAMAM-G3 and
PAMAM-G4) nanoparticles in aqueous solution at physiological pH. Thermodynamic parameters …
PAMAM-G4) nanoparticles in aqueous solution at physiological pH. Thermodynamic parameters …
Studies on PEGylated and drug-loaded PAMAM dendrimers
G Pan, Y Lemmouchi, EO Akala… - Journal of bioactive and …, 2005 - journals.sagepub.com
… these PEG conjugated PAMAM dendrimers were studied. The percentage coverage of
PAMAM dendrimer surface with PEG had little effect on the encapsulation efficiency but affected …
PAMAM dendrimer surface with PEG had little effect on the encapsulation efficiency but affected …
Intratumor performance and therapeutic efficacy of PAMAM dendrimers carried by clustered nanoparticles
… efficacy in an orthotopic pancreatic tumor model. The mechanistic study revealed that G3-PAMAM …
weak cell internalization, while G7-PAMAM was much less penetrative because of its …
weak cell internalization, while G7-PAMAM was much less penetrative because of its …
Dendrimer-based nanocarriers demonstrating a high efficiency for loading and releasing anticancer drugs against cancer cells in vitro and in vivo
… PAMAM dendrimer G 2.5 were prepared for loading anticancer drugs. For loading cisplatin,
carboxylated dendrimer … Pegylated PAMAM dendrimers (G 3.0) were synthesized below 40 …
carboxylated dendrimer … Pegylated PAMAM dendrimers (G 3.0) were synthesized below 40 …
PEGylated PAMAM dendrimers loading oxaliplatin with prolonged release and high payload without burst effect
MN Ho, LG Bach, DH Nguyen, CH Nguyen… - …, 2019 - Wiley Online Library
… To explore the oxaliplatin carrying ability of PEGylated dendrimer G4.0, drug loading efficiency
(DLE) was determined, and the oxaliplatin releasing kinetic was investigated. To evaluate …
(DLE) was determined, and the oxaliplatin releasing kinetic was investigated. To evaluate …
Poly (amidoamine)(PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy
J Li, H Liang, J Liu, Z Wang - International journal of pharmaceutics, 2018 - Elsevier
… Moreover, the secondary interactions between the PAMAM dendrimers and the loaded …
uptake of siRNA and higher loading efficiency for doxorubicin. In another important study, …
uptake of siRNA and higher loading efficiency for doxorubicin. In another important study, …
Co-delivery of doxorubicin and TRAIL plasmid by modified PAMAM dendrimer in colon cancer cells, in vitro and in vivo evaluation
E Pishavar, M Ramezani, M Hashemi - Drug Development and …, 2019 - Taylor & Francis
… Drug loading into modified PAMAM In order to increase transfection efficiency and loading
capacity of PAMAM dendrimer as a co-delivery system, 10-bromodecanoic acid, PEG, and …
capacity of PAMAM dendrimer as a co-delivery system, 10-bromodecanoic acid, PEG, and …
相关搜索
- pegylated pamam dendrimers
- pamam dendrimers drug delivery system
- drug loading efficacy dendrimer morphology
- pamam dendrimers therapeutic efficacy
- pamam dendrimer complexes
- cytotoxicity of pamam dendrimers
- pamam dendrimer nanomolecules
- characterization of a pamam dendrimer nanocarrier
- pamam dendrimer nanoclusters
- modified pamam dendrimer
- polymer morphology loading efficacy
- pamam dendrimers gene delivery nanosystems
- pamam dendrimers target therapy
- cancer diagnosis and therapy pamam dendrimer
- pamam dendrimers surface acetylation
- pamam dendrimers transfection efficiencies