BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications

KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
… the most rapidly increasing cancer among women and the … thyroid cancers are classified
into papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer

BRAF mutations are associated with some histological types of papillary thyroid carcinoma

V Trovisco, I Vieira de Castro, P Soares… - The Journal of …, 2004 - Wiley Online Library
… Mutations in the BRAF gene have recently been detected in a wide range of neoplastic …
in melanoma and papillary thyroid carcinoma (PTC). The hot-spot mutation BRAF V599E is …

BRAF V600E mutation and Its Association with Clinicopathological Features of Papillary Thyroid Cancer: A Meta-Analysis

C Li, KC Lee, EB Schneider… - The Journal of Clinical …, 2012 - academic.oup.com
… terms BRAF mutation and papillary thyroid cancer and any terms associated with disease
prognosis: … significance of BRAF mutation by examining the association between BRAF V600E …

Optimizing surgical treatment of papillary thyroid carcinoma associated with BRAF mutation

L Yip, MN Nikiforova, SE Carty, JH Yim, MT Stang… - Surgery, 2009 - Elsevier
BRAF oncogene is the most common genetic alteration found in papillary thyroid carcinoma
(PTC) and is associated with extrathyroidal extension, lymph node metastasis, and tumor

BRAF mutation associated with other genetic events identifies a subset of aggressive papillary thyroid carcinoma

AM Costa, A Herrero, MF Fresno… - Clinical …, 2008 - Wiley Online Library
BRAF V600E mutation represents the most common oncogenic event in sporadic papillary
thyroid cancer (PTC… Moreover, the impact of BRAF V600E mutants on tumour-related patient's …

Higher rate of BRAF mutation in papillary thyroid cancer over time A single‐institution study

A Mathur, W Moses, R Rahbari, E Khanafshar… - Cancer, 2011 - Wiley Online Library
… In conclusion, we found higher rates of BRAF V600E mutation over a 15-year period. …
papillary thyroid cancer thus may contribute to the increasing incidence of papillary thyroid cancer. …

Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers

H Namba, M Nakashima, T Hayashi… - The Journal of …, 2003 - academic.oup.com
cancers. The aim of the present study was to determine the frequency of BRAF mutations in
thyroid cancer … We analyzed exons 11 and 15 of BRAF gene in six human thyroid cancer cell …

BRAF mutations are uncommon in papillary thyroid cancer of young patients

K Penko, J Livezey, C Fenton, A Patel, D Nicholson… - Thyroid, 2005 - liebertpub.com
BRAF gene sequence in thyroid cancers specifically obtained from patients younger than
21 years of age. Analysis of thyroid cancers … when matched for similar stage of disease (1–3). …

BRAF mutation in thyroid cancer

M Xing - Endocrine-related cancer, 2005 - erc.bioscientifica.com
… epithelial cell-derived papillary thyroid cancer (PTC), follicular thyroid cancer (FTC),
anaplastic thyroid cancer (ATC), and para-follicular C-cell-derived medullary thyroid cancer (MTC), …

BRAF Mutation Testing of Thyroid Fine-Needle Aspiration Biopsy Specimens for Preoperative Risk Stratification in Papillary Thyroid Cancer

M Xing, D Clark, H Guan, M Ji, A Dackiw… - Journal of Clinical …, 2009 - ascopubs.org
… This study investigated the utility of BRAF mutation testing of thyroid fine-needle aspiration
biopsy (FNAB) specimens for preoperative risk stratification in papillary thyroid cancer (PTC). …