BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer
… BRAF V600E, through overactivating the … that BRAF V600E might play an important role in
LNM-related mortality risk in PTC, thus differentiating LNM in wild-type BRAF PTC and BRAF-…
LNM-related mortality risk in PTC, thus differentiating LNM in wild-type BRAF PTC and BRAF-…
BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas
MN Nikiforova, ET Kimura, M Gandhi… - The Journal of …, 2003 - academic.oup.com
… the BRAF gene has been identified as the most common genetic event in papillary thyroid
carcinoma (9… Here, we demonstrate that progression from papillary thyroid carcinoma to poorly …
carcinoma (9… Here, we demonstrate that progression from papillary thyroid carcinoma to poorly …
Both BRAF V600E Mutation and Older Age (≥65 Years) are Associated with Recurrent Papillary Thyroid Cancer
GM Howell, SE Carty, MJ Armstrong… - Annals of surgical …, 2011 - Springer
… features of BRAF-positive papillary thyroid cancer (PTC) and association with age. … BRAF
mutation and more aggressive tumor behavior is limited to older patients, and therefore BRAF …
mutation and more aggressive tumor behavior is limited to older patients, and therefore BRAF …
BRAF is a therapeutic target in aggressive thyroid carcinoma
G Salvatore, V De Falco, P Salerno, TC Nappi… - Clinical Cancer …, 2006 - AACR
… In papillary thyroid carcinomas, this mutation is associated … BRAF as a potential therapeutic
target for thyroid carcinoma. … (c) papillary thyroid carcinoma with the V600E BRAF mutation …
target for thyroid carcinoma. … (c) papillary thyroid carcinoma with the V600E BRAF mutation …
Is BRAF mutation associated with lymph node metastasis in patients with papillary thyroid cancer?
KC Lee, C Li, EB Schneider, Y Wang, H Somervell… - Surgery, 2012 - Elsevier
… variant papillary thyroid cancers, which traditionally are not BRAF positive. I think that that
accounts for why we also have a higher percentage of BRAF … the utility of BRAF in the long run. …
accounts for why we also have a higher percentage of BRAF … the utility of BRAF in the long run. …
Presence of BRAF V600E in Very Early Stages of Papillary Thyroid Carcinoma
C Ugolini, R Giannini, C Lupi, G Salvatore, P Miccoli… - Thyroid, 2007 - liebertpub.com
… thyroid conditions. Morphologically, these malignancies have virtually always features of
differentiated papillary thyroid carcinoma (… BRAF(V600E) mutation has emerged as the most …
differentiated papillary thyroid carcinoma (… BRAF(V600E) mutation has emerged as the most …
BRAF and RAS Mutations in Follicular Variants of Papillary Thyroid Carcinoma
… It has been reported that prevalence (80 to 90 %) of BRAF V600E mutation in papillary
thyroid carcinoma in Korean patient was higher than that (approximately 45 %) of Western …
thyroid carcinoma in Korean patient was higher than that (approximately 45 %) of Western …
BRAF and NRAS Mutations in Papillary Thyroid Carcinoma and Concordance in BRAF Mutations Between Primary and Corresponding Lymph Node Metastases
N Fakhruddin, M Jabbour, M Novy, H Tamim… - Scientific reports, 2017 - nature.com
… High prevalence and possible de novo formation of BRAF mutation in metastasized
papillary thyroid cancer in lymph nodes. J Clin Endocrinol Metab 90, 5265–5269, doi:10.1210/jc.…
papillary thyroid cancer in lymph nodes. J Clin Endocrinol Metab 90, 5265–5269, doi:10.1210/jc.…
Quantification of BRAF V600E alleles predicts papillary thyroid cancer progression
… V600E mutation is the most common genetic alteration in thyroid cancer. However, its …
of BRAF V600E and the clinicopathological features of classic papillary thyroid carcinoma (PTC). …
of BRAF V600E and the clinicopathological features of classic papillary thyroid carcinoma (PTC). …
[HTML][HTML] BRAF-activated LncRNA functions as a tumor suppressor in papillary thyroid cancer
T Liao, N Qu, RL Shi, K Guo, B Ma, YM Cao, J Xiang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… selective inhibitor U0126, without altering BRAF's effects in wild-type … BRAF V600E -positive
thyroid cancer. In this study, we report that BRAF-activated BANCR may function as a tumor …
thyroid cancer. In this study, we report that BRAF-activated BANCR may function as a tumor …