… In summary, paravalvular leak is common after surgical and transcatheter valvular interventions.
Early recognition and intervention are imperative for appropriate management of PVL, …

… who have paravalvular regurgitation can be asymptomatic or present with hemolysis or heart
failure, … Compared with performing the procedure in structurally normal hearts, performing …

… This mode of treatment is an initial therapy in most centers with experienced structural heart
… monitoring patients with heart failure. Evaluation of paravalvular leaks using multimodality …

… to review the feasibility and efficacy of the percutaneous device closure of a consecutive
series of patients with paravalvular leaks referred to our Structural Heart Disease Center. …

… closure requires a combination of disease-specific medical knowledge and technical skill.
A comprehensive understanding of valvular and structural heart disease is necessary to guide …

… management of valvular heart disease, percutaneous repair of paravalvular prosthetic valve
… hemolysis or New York Heart Association class III or IV heart failure who are at high risk for …

… The paravalvular defect produces regurgitation, generating volume overload and damage
to red cells while crossing the PVLs, secondary to the shear stress resulting in heart failure …

… disease result in a worse clinical outcome if severe. Minimal-invasive, surgical and/or
catheter-based structural heart disease (… TAVI such as paravalvular leak, conductance …

… smaller paravalvular defects whereas larger defects are typically associated with heart failure.
… in relation to the sewing ring, prosthetic valve leaflets or discs, and subvalvular structures …

… Although we used this technique only for paravalvular leak and LV pseudoaneurysm
closure, it may have application for other percutaneous structural heart interventions. …