Mechanisms of particulate matter toxicity

S Salvi, ST Holgate - Clinical and experimental allergy, 1999 - search.ebscohost.com
… mass is the primary determinant of the acute inflammatory response for both the ambient
and combustion source particulate matter samples [77]. Recently, particles from …

Inflammatory health effects of indoor and outdoor particulate matter

W Wu, Y Jin, C Carlsten - Journal of Allergy and Clinical Immunology, 2018 - Elsevier
… that all combustion-derived particulate matter (PM) is inflammatory to some extent in the lungs
… The inflammatory response is believed to be a major biologic mechanism underlying PM …

Neurogenic inflammation and particulate matter (PM) air pollutants

B Veronesi, M Oortgiesen - Neurotoxicology, 2001 - Elsevier
… The studies described in this review propose a mechanism by which neurogenic elements
initiate and sustain PM-mediated airway inflammation. Such neurogenic influences have …

Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms

GRS Budinger, JL McKell, D Urich, N Foiles, I Weiss… - PloS one, 2011 - journals.plos.org
Background Exposure of human populations to ambient particulate matter (PM) air pollution
significantly contributes to the mortality attributable to ischemic cardiovascular events. We …

Fine particulate matter air pollution and atherosclerosis: mechanistic insights

Y Bai, Q Sun - Biochimica et Biophysica Acta (BBA)-General Subjects, 2016 - Elsevier
… In order to clarify the molecular mechanisms of each step, we individually discussed these
… PM 2.5 -mediated inflammation both locally and systemically is a major mechanism by which …

Inflammatory cell signaling following exposures to particulate matter and ozone

Z Yan, Y Jin, Z An, Y Liu, JM Samet, W Wu - Biochimica et Biophysica Acta …, 2016 - Elsevier
… Recent studies seeking to determine the receptors and intracellular signaling mechanisms
for air pollutant-induced inflammatory response in airway cells have implicated pattern …

Insights in particulate matter‐induced allergic airway inflammation: focus on the epithelium

KC De Grove, S Provoost, GG Brusselle… - Clinical & …, 2018 - Wiley Online Library
… (SO 2 ), biological substances and particulate matter (PM), derived from natural … mechanisms
of PM-induced toxicological effects and their ability to induce lung injury and inflammation.…

Chronic residential exposure to particulate matter air pollution and systemic inflammatory markers

B Hoffmann, S Moebus, N Dragano… - Environmental …, 2009 - ehp.niehs.nih.gov
… ; however, our findings warrant further investigations of sex-specific mechanisms and
other individual characteristics that may play a role in the induction of chronic inflammation. …

Effects of particulate matter on inflammatory markers in the general adult population

DH Tsai, N Amyai, P Marques-Vidal, JL Wang… - Particle and fibre …, 2012 - Springer
… Although the precise mechanisms underlying this association are still unclear, the induction
of systemic inflammation following particle inhalation represents a plausible mechanistic …

Particulate matter in COPD pathogenesis: an overview

M Kaur, J Chandel, J Malik, AS Naura - Inflammation Research, 2022 - Springer
… , a potential role of air pollution particularly particulate matter (PM) in COPD development
has … player in orchestrating COPD inflammatory cycle but the exact molecular mechanism(s) …