… patients with more severe COPD. This article reviews the evidence for treatment strategies
used in COPD with a focus on combination therapies … Spiriva in Patients With Severe COPD) …

… (LAMA) and long-acting beta-agonist (LABA) combination therapy has been recommended
for patients with COPD who have severe symptoms and a history of exacerbations because it …

… preventing COPD exacerbations based on the rank statistics. Combination therapies appear
… We did not consider triple combination therapy (ie LABA/LAMA/ICS) because it was out of …

… Combination therapy and monotherapy showed no clear difference in the … of COPD-related
bad days or exacerbation days. Significantly fewer patients treated with combination therapy …

… suggest that combination therapy with salmeterol and theophylline may provide substantial
benefits in both physiologic and clinical outcomes in symptomatic patients with COPD. …

… In a study of 20 patients with COPD, Grassi … combination therapy in COPD is for bronchodilator
reversibility testing. In two multicenter, 3-mo, randomized controlled trials, 1,067 patients …

… In conclusion, each COPD patient is different. The response to the inhaled combination
therapy can depend on several factors (stage, concomitant diseases, method of inhalation, …

… may increase the risk of cardiovascular disease in patients with COPD. The aim of this … /LABA
combination therapy modifies the risk of cardiovascular disease in patients with COPD. …

… management of COPD and as such, LABA/LAMA combination therapy could play an … and
dyspnoea in patients with COPD. The last item is particularly important in those patients with …

… combination to treat patients with COPD with high blood eosinophil count, 7 whereas, and
as expected, in this meta-analysis, the efficacy of adding a LAMA to an ICS/LABA combination …