Characterization of the peripheral action of neurokinins and neurokinin receptor selective agonists on the rat cardiovascular system
R Couture, O Laneuville, C Guimond… - Naunyn-Schmiedeberg's …, 1989 - Springer
… , neurokinin A (NKA), neurokinin B (NKB) and selective agonists for neurokinin receptors were
… Neurokinins (NKs) elicited a vasodepressor effect with the following rank order of potency: …
… Neurokinins (NKs) elicited a vasodepressor effect with the following rank order of potency: …
Neurokinin-receptor antagonists: pharmacological tools and therapeutic drugs
J Longmore, RG Hill… - Canadian journal of …, 1997 - cdnsciencepub.com
… the actions of tachykinins released from peripheral nerves, and for the NK1-receptor antagonists
(… studied class of neurokinin-receptor antagonists) central sites of action have also been …
(… studied class of neurokinin-receptor antagonists) central sites of action have also been …
Peripheral tachykinin receptors as targets for new drugs
R Patacchini, CA Maggi - European journal of pharmacology, 2001 - Elsevier
… Owing to the lack of PPT-II gene expression in peripheral tissues, substance P and
neurokinin A are the only tachykinins detected in appreciable amounts at this level. In normal, …
neurokinin A are the only tachykinins detected in appreciable amounts at this level. In normal, …
Pharmacology of neurokinin receptors
D Regoli, F Nantel - Biopolymers: Original Research on …, 1991 - Wiley Online Library
… The study of those three receptors was made possible by the use of peripheral tissues that
contain only one neurokinin receptor type. They were characterized by the use of neurokinins, …
contain only one neurokinin receptor type. They were characterized by the use of neurokinins, …
Pharmacological receptors for substance P and neurokinins
D Regoli, G Drapeau, S Dion, P D'Orléans-Juste - Life sciences, 1987 - Elsevier
… Substance P (SP), neurokinin A (NKA) and neurokinin B (NKB) (… in peripheral nerves to
exert distinct peripheral actions. … Selectivity of action may in part be provided by the peripheral …
exert distinct peripheral actions. … Selectivity of action may in part be provided by the peripheral …
A differentiation between peripheral and central neurokinin receptors using phenoxybenzamine
JL Vaught, RW Scott, HI Jacoby - European journal of pharmacology, 1986 - Elsevier
… peripheral receptors. We now report a differentiation of peripheral and central neurokinin
receptors by … indicates the existence of a distinct neurokinin B receptor in the mouse spinal cord …
receptors by … indicates the existence of a distinct neurokinin B receptor in the mouse spinal cord …
Neurokinin-1 receptor in peripheral nerve terminals mediates thermal hyperalgesia
WL Chen, YQ Zhang, ZQ Zhao - Biochemical and biophysical research …, 2006 - Elsevier
… Neurokinin-1 receptor (NK-1) plays an important role in … explore whether activation of peripheral
NK-1 receptor, especially … NK-1 receptors expressed on the peripheral afferent terminals …
NK-1 receptor, especially … NK-1 receptors expressed on the peripheral afferent terminals …
Neurokinin receptor antagonists
CJ Swain - Progress in medicinal chemistry, 1998 - books.google.com
… In contrast to the excellent activity of LY303870 in peripheral assays of NK1 receptor function,
very high doses were required to obtain activity in CNS assays [51]. Doses of up to 30 mg/…
very high doses were required to obtain activity in CNS assays [51]. Doses of up to 30 mg/…
Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues
PW Mantyh, T Gates, CR Mantyh… - Journal of …, 1989 - Soc Neuroscience
… Quantitative receptor autoradiography … peptide receptor binding sites in rat CNS and
peripheral tissues. … Neurokinin-a, neurokinin A, and neuromedin L are alternative names for …
peripheral tissues. … Neurokinin-a, neurokinin A, and neuromedin L are alternative names for …
Role of neurokinin type 1 receptor in nociception at the periphery and the spinal level in the rat
… neurokinin type 1 receptor (NK1r) and sensitises the dorsal horn neurons. SP is also released
from the peripheral … However, their individual contribution at spinal and peripheral levels to …
from the peripheral … However, their individual contribution at spinal and peripheral levels to …
相关搜索
- spinal action of neurokinins receptor mechanism
- neurokinin receptor antagonists
- neurokinin receptor subtypes
- neurokinin receptors selective agonists
- pharmacology of neurokinin receptors
- neurokinin receptor rat cardiovascular system
- peripheral tachykinin receptors
- receptors for neurokinins peripheral organs
- related neurokinins receptors for substance
- peripheral nerve terminals neurokinin 1 receptor
- neurokinin 1 receptor gene expression
- neurokinin 1 receptor knockout mice
- neurokinin type 1 receptor
- heat stimuli neurokinin 1 receptors
- neurokinin receptors various isolated organs
- neurokinin receptor therapeutic drugs