… dendrimer molecule. In the present study we investigated the potential of PAMAM dendrimers
to increase the solubility of … The solubility of ibuprofen in G4 PAMAM dendrimer solutions in …

… not freely soluble in water and creates gastrointestinal problems. In the present study we
investigated the potential of polyamidoamine (PAMAM) dendrimers to increase the solubility of …

… [7,8], polyamidoamine (PAMAM) dendrimers have gained significant attention in biomedical
… as solubility enhancers of poorly soluble molecules [2,3]. Though PAMAM dendrimers bear …

… than lower ones, whereas lower generation dendrimers are much easier for electrostatic
attachment … much more to the solubility enhancement of poorly soluble drugs than hydrophobic …

… dendrimers as a solubility enhancer. PTX encapsulation into polyglycerol dendrimers resulted
in 400-fold improved water solubility … However, most dendrimer-related formulations utilize …

… the solubility of different classes of drugs. This chapter had been focused on the solubility
enhancement of drug candidates with special emphasis on the dendrimer-based formulation. …

… gels the dendrimers may function as solubility enhancers by … The resultant solubility
enhancement allows the presentation … widely investigated as penetration enhancers for topical …

… Outside this conceptual framework, VAR-polyamidoamine (PAMAM) dendrimer complexes
… PAMAM dendrimers are considered as a unique class of synthetic polymers characterized …

… into the dendrimer depending on environmental properties. If the drug molecules were poorly
soluble in water, but the dendrimer … , the drug would prefer partitioning to the dendrimer. …

… Further, the solubilization potential of the dendrimers was compared … enhancement
potential of the dendrimers was investigated after oral and topical administration of drug-dendrimer …