… ie, water solubility and drug permeability. The main drawback with oral route is poor
bioavailability which is due to poor solubility and permeability. Poor soluble drugs usually require …

… in formulations of poorly water-soluble drugs to enhance their … The benefits of mesoporous
materials in drug delivery … to produce hybrid materials with poorly soluble compounds, and …

… Likewise, artificial surfactants such as sodium lauryl sulfate (SLS) are routinely added to
the dosage form to increase the apparent aqueous solubility of poorly soluble drugs. …

… toward solubility enhancement of a poorly water-soluble molecule typically … poorly
water-soluble drugs. One faced with the challenge of developing a drug product from a poorly …

… loaded with a variety of poorly soluble drugs including anticancer drugs, such as taxol and
… are capable of delivering their load even into poorly permeable tumors in mice with a higher …

… the solubility and bioavailability of poorly soluble drugs. In … of the solubility and dissolution
rates of poorly soluble drugs is … and solution phase interactions on solubility as well as those …

… to achieve the most robust solubility enhancement. … to the solubility and permeability of poorly
soluble drugs from … , although enhancing drug solubility, mostly hamper drug permeation. …

… Solubility is a most important parameter for the oral bioavailability of poorly soluble drugs. …
as examples for the preparation of a poorly soluble drug in a highly water soluble carrier. …

… II drugs with poor solubility and reasonable permeability is limited by the drug dissolution step
from drug products… In view of the increasing market share of oral drug products, a variety of …

With the increasing number of poorly water-soluble compounds in contemporary drug
discovery pipelines, the concept of supersaturation as an effective formulation approach for …