Establishing best practices and guidance in population modeling: an experience with an internal population pharmacokinetic analysis guidance
W Byon, MK Smith, P Chan, MA Tortorici… - CPT …, 2013 - Wiley Online Library
… This tutorial describes the development of a population pharmacokinetic (Pop PK) analysis
guidance within Pfizer, which strives for improved consistency and efficiency, and a more …
guidance within Pfizer, which strives for improved consistency and efficiency, and a more …
Population pharmacokinetic analysis and dosing regimen optimization of meropenem in adult patients
C Li, JL Kuti, CH Nightingale… - The Journal of Clinical …, 2006 - Wiley Online Library
… pharmacokinetic parameters in this population. The objective of the present study was to
develop a population pharmacokinetic … covariates on meropenem pharmacokinetics. In addition…
develop a population pharmacokinetic … covariates on meropenem pharmacokinetics. In addition…
Model‐based population pharmacokinetic analysis of nivolumab in patients with solid tumors
… The clinical pharmacology profile of nivolumab was analyzed by a population pharmacokinetics
model that assessed covariate effects on nivolumab concentrations in 1,895 patients …
model that assessed covariate effects on nivolumab concentrations in 1,895 patients …
Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis
AA Fasanmade, OJ Adedokun, J Ford… - European journal of …, 2009 - Springer
… disease population. It was the aim of this study to evaluate its population pharmacokinetics
in … colitis and characterize patient covariates that affect its disposition in this population. …
in … colitis and characterize patient covariates that affect its disposition in this population. …
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Interpreting population pharmacokinetic‐pharmacodynamic analyses–a clinical viewpoint
SB Duffull, DFB Wright… - British journal of clinical …, 2011 - Wiley Online Library
… of an analysis themselves. Initially we introduce the general framework of population analysis
and … We then follow-up with specific details on how to interpret population analyses for the …
and … We then follow-up with specific details on how to interpret population analyses for the …
Population pharmacokinetic analysis during the first 2 years of life: an overview
A Marsot, A Boulamery, B Bruguerolle… - Clinical pharmacokinetics, 2012 - Springer
… Pharmacokinetic population approaches using sparse sampling may resolve this issue. The
pharmacokinetics … published studies concerning population pharmacokinetic approaches in …
pharmacokinetics … published studies concerning population pharmacokinetic approaches in …
Population pharmacokinetic analysis of voriconazole plasma concentration data from pediatric studies
… This report describes the results of a population pharmacokinetic analysis characterizing
the … The primary aim of our analysis was to construct a refined pharmacokinetic model for …
the … The primary aim of our analysis was to construct a refined pharmacokinetic model for …
Population pharmacokinetics III: design, analysis, and application of population pharmacokinetic studies
EI Ette, PJ Williams, JR Lane - Annals of Pharmacotherapy, 2004 - journals.sagepub.com
OBJECTIVE To present a framework within which population pharmacokinetic (PPK) studies
should be designed and analyzed and discuss the application of developed PPK models. …
should be designed and analyzed and discuss the application of developed PPK models. …
Do we need full compliance data for population pharmacokinetic analysis?
P Girard, LB Sheiner, H Kastrissios… - … of pharmacokinetics and …, 1996 - Springer
… For population pharmacokinetic analysis of multiple oral … that traditional population
pharmacokinetic analysis methods … of initially estimating population pharmacokinetic parameters, …
pharmacokinetic analysis methods … of initially estimating population pharmacokinetic parameters, …
Population pharmacokinetic analysis of anidulafungin, an echinocandin antifungal
JA Dowell, W Knebel, T Ludden… - The Journal of …, 2004 - Wiley Online Library
… The objective of this analysis was to describe the pharmacokinetic characteristics of
anidulafungin in patients with serious fungal disease based on pharmacokinetic data collected …
anidulafungin in patients with serious fungal disease based on pharmacokinetic data collected …