Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design

A Tremoulet, J Le, B Poindexter… - Antimicrobial agents …, 2014 - Am Soc Microbiol
… the population PK of ampicillin in 73 neonates as young as 24 weeks of gestation and up
to 28 days PNA. This broad age spectrum enabled the construction of a population PK model …

Population pharmacokinetics and pharmacodynamic target attainment of ampicillin in neonates with hypoxemic‐ischemic encephalopathy in the setting of controlled …

JJ Cies, KN Fugarolas, WS Moore… - … : The Journal of …, 2017 - Wiley Online Library
… and pharmacodynamic changes in neonates receiving CH. Therefore, the aim of this … the
population pharmacokinetics and pharmacodynamic target attainment of ampicillin in neonates

Population pharmacokinetic models of first choice beta-lactam antibiotics for severe infections treatment: What antibiotic regimen to prescribe in children? What …

A Marsot - Journal of Pharmacy & Pharmaceutical …, 2020 - journals.library.ualberta.ca
… essential medicines for children. Methods… population PK model of piperacillin, amoxicillin,
ampicillin, cefotaxime, ceftriaxone, cloxacillin, imipenem or meropenem in neonates or children

Paradoxical antibiotic effect of ampicillin: use of a population pharmacokinetic model to evaluate a clinical correlate of the eagle effect in infants with bacteremia

…, Best Pharmaceuticals for Children Act … - The Pediatric …, 2020 - journals.lww.com
… analysis is that ampicillin PK parameters were not estimated directly in our study population
but were predicted using a population PK model based on a similar patient population. The …

Population pharmacokinetics and dosing of amoxicillin in (pre) term neonates

J Pullen, LML Stolk, FHM Nieman… - Therapeutic drug …, 2006 - journals.lww.com
… is the major pathway for amoxicillin elimination 3 in (pre)term neonates. The population
pharmacokinetic parameters of amoxicillin found in the present study are similar to the results of …

Comparative analysis of ampicillin plasma and dried blood spot pharmacokinetics in neonates

J Le, B Poindexter, JE Sullivan… - Therapeutic drug …, 2018 - journals.lww.com
… Dried blood spot (DBS) is a practical sampling strategy for pharmacokinetic studies in
neonates. The utility of DBS to determine the population pharmacokinetics (pop-PK) of ampicillin, …

Ampicillin pharmacokinetics during first week of life in preterm and term neonates

H Padari, H Soeorg, T Tasa, T Metsvaht… - The Pediatric …, 2021 - journals.lww.com
… Characterization of the population pharmacokinetics of ampicillin in neonates using an
opportunistic study design. Antimicrob Agents Chemother. 2014; 58:3013–3020. …

Population pharmacokinetics and dosing optimization of amoxicillin in Chinese infants

YE Wu, YK Wang, BH Tang, L Dong, X Li… - The Journal of …, 2021 - Wiley Online Library
… to evaluate the population pharmacokinetics of intravenous amoxicillin in infants and suggest
… Dosage recommendations of amoxicillin for use in infants are extrapolated from ampicillin

Population pharmacokinetics of amoxicillin in term neonates undergoing moderate hypothermia

YA Bijleveld, RAA Mathôt… - Clinical …, 2018 - Wiley Online Library
… As hypothermic treatment can alter the PK of certain drugs,17 studying its potential effect on
… asphyxiated newborns treated with moderate hypothermia and describe the population PK

[PDF][PDF] Clinical pharmacology of ampicillin in neonates and infants: effects and pharmacokinetics

GM Pacifici - International Journal of Pediatrics, 2017 - scholar.archive.org
… the effects and pharmacokinetics of ampicillin in neonates and infants. … ampicillin population
pharmacokinetic parameters for 13 neonates, and Table.2 shows the ampicillin population