Population pharmacokinetics of gentamicin in premature newborns

B García, E Barcia, F Pérez… - Journal of Antimicrobial …, 2006 - academic.oup.com
population pharmacokinetic parameters of gentamicin in a large group of premature neonates
… clinical and physiopathological covariates on the pharmacokinetic profile of the drug. …

Population pharmacokinetics of gentamicin in preterm neonates: evaluation of a once-daily dosage regimen

ML Vervelde, CMA Rademaker… - Therapeutic drug …, 1999 - journals.lww.com
… gentamicin therapy for premature newborns hospitalized in our neonatal intensive care unit.
… we calculated pharmacokinetic parameters in a population of 43 premature newborns using …

Population pharmacokinetic study of gentamicin in a large cohort of premature and term neonates

A Fuchs, M Guidi, E Giannoni, D Werner… - British journal of …, 2014 - Wiley Online Library
… The purpose of this study was to characterize the population PK parameters of gentamicin
in a large cohort of preterm and term neonates and to investigate the influence of clinical, …

Population pharmacokinetics and dosing of flucloxacillin in preterm and term neonates

J Pullen, L de Rozario, LML Stolk… - Therapeutic drug …, 2006 - journals.lww.com
… The population pharmacokinetic parameters of flucloxacillin in the present study differ from
the population pharmacokinetic parameters found by Herngren et al. CL/W (0.04 L kg −1 h −1 …

Predicting neonatal pharmacokinetics from prior data using population pharmacokinetic modeling

J Wang, AN Edginton, D Avant… - The Journal of Clinical …, 2015 - Wiley Online Library
… Selection of the first dose for neonates in clinical trials is very challenging. … if a population
pharmacokinetic (PK) model developed with data from infants to adults is predictive of neonatal

Developmental pharmacokinetics of gentamicin in preterm and term neonates: population modelling of a prospective study

EI Nielsen, M Sandström, PH Honoré, U Ewald… - … pharmacokinetics, 2009 - Springer
… This study was performed to characterize the population pharmacokinetics of gentamicin
in preterm and term neonates and to identify and quantify relationships between patient …

Population pharmacokinetics and dosing optimization of amoxicillin in neonates and young infants

BH Tang, YE Wu, C Kou, YJ Qi, H Qi… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… a few preterm neonates. Thus, we aimed to evaluate the population pharmacokinetics of …
size covering the entire age range of neonates and young infants and to establish evidence-…

Population pharmacokinetics and dosing regimen design of milrinone in preterm infants

M Paradisis, X Jiang, AJ McLachlan, N Evans… - … -Fetal and Neonatal …, 2007 - fn.bmj.com
… : Population pharmacokinetic modelling in the preterm infant … of pharmacokinetic studies in
neonatal clinical pharmacology. … on the pharmacokinetics of milrinone in very preterm infants. …

Population pharmacokinetics of teicoplanin in preterm and term neonates: is it time for a new dosing regimen?

A Kontou, K Sarafidis, O Begou, HG Gika… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
… to develop a population pharmacokinetic (PK) model in … preterm neonates. By using an
optimal design approach, a prospective PK study was designed and implemented in 60 neonates

Recently registered midazolam doses for preterm neonates do not lead to equal exposure: a population pharmacokinetic model

S Völler, RB Flint, F Beggah, I Reiss… - The Journal of …, 2019 - Wiley Online Library
… developed a population pharmacokinetic model for midazolam in preterm neonates with a
… was it possible to develop a population pharmacokinetic model of this drug. Although the …