Developmental pharmacokinetics in neonates
K Allegaert, M Rayyan, S Vanhaesebrouck… - Expert review of …, 2008 - Taylor & Francis
… The legal initiatives, including Paediatric Drug Regulation in the EU, and effective research
tools, including population pharmacokinetics, are two important stimulants to boost further …
tools, including population pharmacokinetics, are two important stimulants to boost further …
Lidocaine (lignocaine) dosing regimen based upon a population pharmacokinetic model for preterm and term neonates with seizures
MPH van den Broek, ADR Huitema… - … pharmacokinetics, 2011 - Springer
… a population pharmacokinetic model for lidocaine for the treatment of neonatal seizures
that … therapy, which was able to describe both preterm and term neonates with a PNA of 0–10 …
that … therapy, which was able to describe both preterm and term neonates with a PNA of 0–10 …
Caffeine citrate treatment for extremely premature infants with apnea: population pharmacokinetics, absolute bioavailability, and implications for therapeutic drug …
BG Charles, SR Townsend, PA Steer… - Therapeutic drug …, 2008 - journals.lww.com
… and bioavailability of caffeine in extremely premature infants undergoing extubation has …
develop a population pharmacokinetic model for caffeine in extremely low birth weight infants. A …
develop a population pharmacokinetic model for caffeine in extremely low birth weight infants. A …
Population pharmacokinetic analysis of ibuprofen enantiomers in preterm newborn infants
N Gregoire, L Desfrere, JC Roze… - The Journal of …, 2008 - Wiley Online Library
… develop and validate a population pharmacokinetic model for R… 24-hour intervals to preterm
newborn infants aged from <6 hours … The aim of the present pharmacokinetic analysis was to …
newborn infants aged from <6 hours … The aim of the present pharmacokinetic analysis was to …
Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design
A Tremoulet, J Le, B Poindexter… - Antimicrobial agents …, 2014 - Am Soc Microbiol
… The population PK parameter estimate for elimination half-life in the present study … premature
neonates, with inverse proportionality to PNA (2, 4, 8). In our cohort of premature neonates, …
neonates, with inverse proportionality to PNA (2, 4, 8). In our cohort of premature neonates, …
Population pharmacokinetics of piperacillin/tazobactam in neonates and young infants
Z Li, Y Chen, Q Li, D Cao, W Shi, Y Cao, D Wu… - European journal of …, 2013 - Springer
… piperacillin/tazobactam population PK model generated in our study provided a rational
basis for the development of preliminary dosing guidelines to neonates and infants less than 2 …
basis for the development of preliminary dosing guidelines to neonates and infants less than 2 …
Population pharmacokinetics and dosing optimization of azlocillin in neonates with early-onset sepsis: a real-world study
YE Wu, T Wang, HL Yang, BH Tang… - Journal of …, 2021 - academic.oup.com
… use in neonates by overcoming … population pharmacokinetics of azlocillin in neonates
using real-world data, to make subsequent dose recommendations and to test these in neonates …
using real-world data, to make subsequent dose recommendations and to test these in neonates …
The role of population pharmacokinetic analysis in rational antibiotic therapy in neonates
… This article summarises the published population PK studies of antibiotics used in neonates.
Our literature search was based on the results of a recent point prevalence study where 12 …
Our literature search was based on the results of a recent point prevalence study where 12 …
Population pharmacokinetics of amoxicillin in term neonates undergoing moderate hypothermia
YA Bijleveld, RAA Mathôt… - Clinical …, 2018 - Wiley Online Library
… The pharmacokinetics (PK) of amoxicillin in asphyxiated newborns undergoing moderate
hypothermia were quantified using prospective data (N = 125). The population PK was …
hypothermia were quantified using prospective data (N = 125). The population PK was …
Population pharmacokinetic analysis of vancomycin in neonates. A new proposal of initial dosage guideline
MR Marqués‐Miñana, A Saadeddin… - British journal of clinical …, 2010 - Wiley Online Library
… to determine population pharmacokinetic parameters of vancomycin in neonatal patients …
-clavulanic acid and spironolactone on the pharmacokinetics of vancomycin in this cohort of …
-clavulanic acid and spironolactone on the pharmacokinetics of vancomycin in this cohort of …