Therapeutic targets in sepsis: past, present, and future
EJ Seeley, GR Bernard - Clinics in Chest Medicine, 2016 - chestmed.theclinics.com
… evolution of sepsis therapy (Table 1) and identifies possible causes for why rational therapies
failed in human trials. In addition, this article examines potential future sepsis targets and …
failed in human trials. In addition, this article examines potential future sepsis targets and …
The pathogenesis of sepsis and potential therapeutic targets
M Huang, S Cai, J Su - International journal of molecular sciences, 2019 - mdpi.com
… brings about abnormal apoptosis in sepsis animals, suggesting that ER stress-mediated
apoptosis represents a potential new target for clinical prevention and treatment for sepsis. …
apoptosis represents a potential new target for clinical prevention and treatment for sepsis. …
Recent advances in sepsis research: novel biomarkers and therapeutic targets
B Ivady, BJ Beres, D Szabo - Current medicinal chemistry, 2011 - ingentaconnect.com
… potential therapeutic targets that may represent new and promising directions for researcher
of sepsis … as markers and therapeutic target points in the treatment of sepsis. Abbreviations: …
of sepsis … as markers and therapeutic target points in the treatment of sepsis. Abbreviations: …
Emerging therapeutic targets for sepsis
EW Tindal, BE Armstead, SF Monaghan… - … on therapeutic targets, 2021 - Taylor & Francis
… In summary, while the innate immune system is rich in potential therapeutic targets and
remains a promising area of research, as has been demonstrated by the study of cytokines in this …
remains a promising area of research, as has been demonstrated by the study of cytokines in this …
Recent developments in the identification of novel therapeutic targets for the treatment of patients with sepsis and septic shock
J Cohen - Scandinavian journal of infectious diseases, 2003 - Taylor & Francis
… As our understanding of the complexity of the host response to sepsis has grown, so too has
the list of potential targets. Some of these are certainly ‘immunological’, although not single …
the list of potential targets. Some of these are certainly ‘immunological’, although not single …
Apoptosis in sepsis: a new target for therapeutic exploration
C Oberholzer, A Oberholzer, M Clare-Salzler… - The FASEB …, 2001 - Wiley Online Library
… apoptosis, represent an attractive therapeutic target for the septic patient. In the current review,
… apoptotic pathways in sepsis syndrome and propose several potential therapeutic targets. …
… apoptotic pathways in sepsis syndrome and propose several potential therapeutic targets. …
New therapies for sepsis
A Cunnington, S Nadel - Current topics in medicinal chemistry, 2008 - ingentaconnect.com
… Statins may be beneficial in prevention of sepsis and as adjunctive treatments. … in severe
sepsis. Many other molecular targets have been identified for possible therapeutic intervention, …
sepsis. Many other molecular targets have been identified for possible therapeutic intervention, …
Novel therapeutic targets for sepsis: regulation of exaggerated inflammatory responses
… provide therapeutic benefits for septic clinical settings. In this concise review, we described
novel potential … , and may shed light on novel therapeutic targets for the treatment of sepsis. …
novel potential … , and may shed light on novel therapeutic targets for the treatment of sepsis. …
Gases in sepsis: novel mediators and therapeutic targets
Z Zhu, S Chambers, Y Zeng, M Bhatia - International Journal of Molecular …, 2022 - mdpi.com
… evidence that points to the potential effects of these gaseous … sepsis/septic shock. Additionally,
we seek to briefly discuss the prospect of developing therapeutic interventions for sepsis …
we seek to briefly discuss the prospect of developing therapeutic interventions for sepsis …
An ongoing search for potential targets and therapies for lethal sepsis
… Therapeutic efficacy of HMGB1-inhibiting herbs Current sepsis therapies are largely …
drugs (eg, hydrocortisone) and early goal-directed therapies (EGDT). For instance, appropriate …
drugs (eg, hydrocortisone) and early goal-directed therapies (EGDT). For instance, appropriate …
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