… -brain barrier permeable metals chelators can be potential therapeutic agents in the treatment
of … of new iron chelators that could potentially be used in novel chelation therapies for the …

… and chelate intracellular iron pools. These studies have led to the development of other iron
chelators that are far more effective than desferrioxamine. Some of these chelators such as 3…

… use of natural iron chelators as therapeutic agents; however, … alteration of pharmacokinetics
of therapeutic drugs, increased … as iron chelators and their therapeutic applications. They are …

… , which increase iron loading, are … potential iron chelators can be evaluated, using
appropriate screening systems, and discuss their potential applications in the chelation of both iron …

… However, unlike haemochromatosis, venesection is not a therapeutic option, and iron
chelation is the only … complex) in order to increase the efficacy and safety of therapeutic agents. …

… This property reduces the potential of iron redistribution. However, DFO is far from being an
ideal therapeutic agent due to its oral inactivity and rapid renal clearance (plasma half-life of …

… modulate iron accumulation in the brain. Therefore, the development of novel iron chelators
as neuroprotective agents … Several iron chelators including 8-hydroxyquinoline derivatives, …

… As a result of this potential toxicity, selective iron chelators … There is also evidence that iron
chelators may minimise the … Non-haem iron enzymes can also be inhibited by iron chelators …

… A number of iron-chelating agents are currently being considered as orally active alternatives
to desferrioxamine (DFO), the therapeutic agent for the treatment of body iron overload that …

… transfer iron and excrete it from the body. Thus, the use of iron chelators as therapeutic agents
… This review investigates the function of various iron chelators in treating iron overload in …