Recombinant SARS-CoV-2 genomes circulated at low levels over the first year of the pandemic
… recombinant SARS-CoV-2 genomes, they represent an extremely small fraction of the
genomes … Although our de novo mutation filtering is likely removing some true recombinant …
genomes … Although our de novo mutation filtering is likely removing some true recombinant …
[HTML][HTML] Recombinant SARS-CoV-2 genomes are currently circulating at low levels
… of putative recombinants, we next sought to use these sequences to ask whether recombination
hotspots in the SARS-CoV-2 genome may be apparent. The limited genome diversity …
hotspots in the SARS-CoV-2 genome may be apparent. The limited genome diversity …
Generation and transmission of interlineage recombinants in the SARS-CoV-2 pandemic
… To identify putative SARS-CoV-2 recombinant viruses, we carried out an analysis of all
complete UK SARS-CoV-2 genomes that had been assigned to lineage B.1.1.7 and that showed …
complete UK SARS-CoV-2 genomes that had been assigned to lineage B.1.1.7 and that showed …
A comparative recombination analysis of human coronaviruses and implications for the SARS-CoV-2 pandemic
… Specifically, we aimed to identify the frequency and genomic location of recombination …
Among SARS-CoV-2 genomes, we detected a total of 8 recombination events detected by at least …
Among SARS-CoV-2 genomes, we detected a total of 8 recombination events detected by at least …
On the origin and evolution of SARS-CoV-2
… mutational variability into this genome, increasing opportunities for future recombination. …
on their genomic position in the SARS-CoV-2 genome model (top panel). b Two scenarios …
on their genomic position in the SARS-CoV-2 genome model (top panel). b Two scenarios …
Genome‐based comparison between the recombinant SARS‐CoV‐2 XBB and its parental lineages
… In conclusion, the genome-based survey of the SARS-CoV-2 recombinat XBB and on its first
sublineage XBB.1 suggest that, although this new lineage presents several spike mutations …
sublineage XBB.1 suggest that, although this new lineage presents several spike mutations …
Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes
… SARS-CoV-2 infection and associated COVID-19. … recombinant SARS-CoV-2 (rSARS-CoV-2)
constructs expressing fluorescent (Venus and mCherry) or luciferase (Nluc) reporter genes …
constructs expressing fluorescent (Venus and mCherry) or luciferase (Nluc) reporter genes …
Pandemic-scale phylogenomics reveals the SARS-CoV-2 recombination landscape
… breakpoint positions 11 , our data indicates that other biases shape the distribution of
recombination events across the SARS-CoV-2 genome. These could include a neutral mechanistic …
recombination events across the SARS-CoV-2 genome. These could include a neutral mechanistic …
Second-generation SARS-CoV-2 recombinants: Lessons from other viruses
… possible in any RNA virus, the rates of recombination vary markedly among … genomes,
exhibit such low rates of recombination that they are effectively clonal. Although recombination is …
exhibit such low rates of recombination that they are effectively clonal. Although recombination is …
Emergence and widespread circulation of a recombinant SARS-CoV-2 lineage in North America
… Our understanding of the effects of genomic recombination on SARS-CoV-2 fitness and
transmission dynamics is still limited, but genetic exchange has been previously associated with …
transmission dynamics is still limited, but genetic exchange has been previously associated with …
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