… The understanding of the contribution of glial cells and brain-derived inflammatory cytokines
… cerebral cytokines and chemokines, and of microglial activation at the early stage of hepatic …

… liver failure (ALF) is characterized by cerebral edema that results in elevation in intracranial
pressure (ICP). The pathogenesis of cerebral … Her blood pressure was much easier to control …

… be down-regulated in brain extracts from animals with ALF due to ischemic liver failure. EAAT…
injury, the nature of the hepatotoxin appear to determine the systemic cytokine profile of the …

… cell volume regulation in cerebral cortical astrocytes exposed to toxic agents previously
identified in experimental and clinical ALF. Such agents include ammonia, the proinflammatory …

… regulation of cerebral hemodynamics [40] . 84 such cirrhotics were studied by Briegel et al.
[41] . The presence and severity of minimal HE were independent of severity of liver disease …

… the pathogenesis of hepatic encephalopathy and brain edema … microglial activation as well
as the up-regulation of IL-1β, ΙL-6 … However, conclusive evidence for increased brain cytokine …

… between sham-operated control rats and … function of severity of liver failure and were
sensitive to mild hypothermia. Given the similar identity of the increased serum and brain cytokines …

… Hypothermia reduces arterial ammonia concentration and its metabolism in the brain,
and decreases cerebral blood flow, brain cytokine production and the levels of markers of …

… This distinguishes it from other vital organs (eg the brain, heart and lungs) that cannot … ,
liver injury induced by toxins and infectious agents is a much more common cause of liver failure …

… Mitochondrial dysfunction and energy failure culminates in astrocytes failing to regulate their
… ammonia uptake and also through its role in reducing brain cytokine production, OS and …