This article investigates the aqueous solubility of the poorly soluble drug candesartan
cilexetil (CC) in the presence of poly (amidoamine)(PAMAM) dendrimers. The effect of …

The aim of this study was to investigate the effect of low generation (G0–G3)
ethylenediamine (EDA) core poly (amidoamine)(PAMAM) dendrimers on the aqueous …

Together with the permeability, the solubility behavior of a drug is a key determinant of its
oral bioavailability. There have always been certain drugs for which solubility has presented …

In the present study we investigated the effect of polyamidoamine (PAMAM) dendrimers on
the aqueous solubility of aceclofenac. The aqueous solubility of aceclofenac was measured …

Objective: To compare various solubilizing agents for their solubilizing propensity as well as
effect of pH, concentration and time on solubility of a highly hydrophobic drug. Materials and …

In this study, a series of aspartate based dendrimers with different cores were synthesized in
a convergent approach and well characterized by NMR and MS techniques. The aqueous …

In the present study we investigated the effect of ethylenediamine (EDA) core
polyamidoamine (PAMAM) dendrimers on the aqueous solubility of nicotinic acid. The …

Guest–host interactions of candesartan cilexetil (CAND) with cyclodextrins (CyDs) have
been investigated using phase solubility diagrams (PSD), X-ray powder diffractometry …

Dendrimers today are known for their three dimensional, monodispersed, highly branched,
macromolecular nano-scopic architecture with number of reactive end groups. Dendrimers …

Dendrimers are 3D, hyperbranched, tree-like polymers having immense potential in drug
delivery, targeting, diagnosis and as carriers for DNA/gene delivery. Dendrimers have …