We have used direct selections to generate large numbers of mutants of Escherichia coli
defective in the mismatch repair system and have screened these to identify mutants with …

An Escherichia coli K-12 strain was constructed with a chromosomal deletion (mutS Δ 800)
in the mutS gene that produced the removal of the C-terminal 53 amino acids which are not …

DNA mismatch repair in Escherichia coli has been shown to be involved in two distinct
processes: mutation avoidance, which removes potential mutations arising as replication …

The MutS protein of Escherichia coli is part of the dam-directed MutHLS mismatch repair
pathway which rectifies replication errors and which prevents recombination between …

We have previously reported that the Escherichia coli mutator strain mutD5 was defective in
the correction of bacteriophage M13mp2 heteroduplex DNA containing a TG mismatch …

The mismatch repair system is involved in the maintenance of genomic integrity by editing
DNA replication and recombination. However, although most mutations are neutral or …

The Dam-directed post-replicatve mismatch repair system of Escherichia coli removes base
pair mismatches from DNA. The products of the mutH, mutL and mutS genes, among others …

We used the lacI system of Escherichia coli to examine the distribution of base substitution
mutations occurring spontaneously in different mismatch-repair-deficient strains. The …

High-resolution crystal structures have recently been solved for the mismatch binding
protein MutS of Escherichia coli and its Thermus aquaticus homologue; they show how …

Escherichia coli mutator mutD5 is the most potent mutator known. The mutD5 mutation
resides in the dnaQ gene encoding the proofreading exonuclease of DNA polymerase III …