Uptake of Staphylococcus aureus by keratinocytes is reduced by interferon–fibronectin pathway and filaggrin expression

R Miyake, K Iwamoto, N Sakai… - The Journal of …, 2022 - Wiley Online Library
Staphylococcus aureus (S. aureus) is frequently detected in the skin of patients with atopic
dermatitis (AD). AD skin‐derived strains of S. aureus (AD strain) are selectively internalized …

[HTML][HTML] Staphylococcus aureus exploits epidermal barrier defects in atopic dermatitis to trigger cytokine expression

T Nakatsuji, TH Chen, AM Two, KA Chun… - Journal of Investigative …, 2016 - Elsevier
Patients with atopic dermatitis (AD) have an abnormal skin barrier and are frequently
colonized by S. aureus. In this study we investigated if S. aureus penetrates the epidermal …

Staphylococcus aureus from atopic dermatitis skin accumulates in the lysosomes of keratinocytes with induction of IL‐1α secretion via TLR9

M Moriwaki, K Iwamoto, Y Niitsu, A Matsushima… - Allergy, 2019 - Wiley Online Library
Background Staphylococcus aureus (S. aureus) is frequently detected in the skin of patients
with atopic dermatitis (AD), and involved in the flare of AD. There are some evidence …

Staphylococcus aureus inhibits terminal differentiation of normal human keratinocytes by stimulating interleukin-6 secretion

ED Son, HJ Kim, T Park, K Shin, IH Bae, KM Lim… - Journal of …, 2014 - Elsevier
Background Staphylococcus aureus (S. aureus) is found on the skin of approximately 90%
of patients with atopic dermatitis and approximately 20% of apparently healthy subjects. S …

Internalization of Staphylococcus aureus by Human Keratinocytes

S Kintarak, SA Whawell, PM Speight… - Infection and …, 2004 - Am Soc Microbiol
Staphylococcus aureus is among the most important human pathogens and causes various
superficial and systemic infections. The ability of S. aureus to be internalized by, and survive …

Staphylococcus aureus: master manipulator of the skin

MR Williams, T Nakatsuji, RL Gallo - Cell host & microbe, 2017 - cell.com
Skin colonization by Staphylococcus aureus is associated with severity of atopic dermatitis
(AD). Two papers in this issue of Cell Host & Microbe by Nakagawa et al.(2017) and Liu et …

[HTML][HTML] Expression of Staphylococcus aureus virulence factors in atopic dermatitis

SE Poh, WLC Koh, SYD Lim, ECE Wang, YW Yew… - JID Innovations, 2022 - Elsevier
Atopic dermatitis (AD) is a skin inflammatory disease in which the opportunistic pathogen
Staphylococcus aureus is prevalent and abundant. S. aureus harbors several secreted …

Cytokine-mediated crosstalk between keratinocytes and T cells in atopic dermatitis

M Humeau, K Boniface, C Bodet - Frontiers in immunology, 2022 - frontiersin.org
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by barrier
dysfunction, dysregulated immune response, and dysbiosis with increased Staphylococcus …

Staphylococcus aureus in atopic dermatitis: Strain-specific cell wall proteins and skin immunity

K Iwamoto, M Moriwaki, R Miyake, M Hide - Allergology International, 2019 - jstage.jst.go.jp
abstract Atopic dermatitis (AD) is a common chronic skin disease. The presence of the
bacterium Staphylococcus aureus (S. aureus) is frequently detected on skin affected with …

Fibronectin and fibrinogen contribute to the enhanced binding of Staphylococcus aureus to atopic skin

SH Cho, I Strickland, M Boguniewicz… - Journal of Allergy and …, 2001 - Elsevier
Background: Staphylococcus aureus colonizes the skin lesions of more than 90% of patients
with atopic dermatitis (AD). The mechanism for increased S aureus colonization in AD is …