[HTML][HTML] Involvement of the L-arginine/nitric oxide/cyclic GMP/KATP channel pathway and PPARγ receptors in the peripheral antinociceptive effect of carbamazepine

B Ghorbanzadeh, V Kheirandish… - Drug Research, 2019 - thieme-connect.com
Carbamazepine has been shown to exert analgesic effects in clinical and experimental pain
situation. This study was conducted to evaluate its potential peripheral antinociceptive …

Contribution of spinal inhibitory receptors in heterosegmental antinociception induced by noxious stimulation

CH Tambeli, P Quang, JD Levine… - European Journal of …, 2003 - Wiley Online Library
Noxious (ie painful) stimulation in the rat induces profound heterosegmental antinociception
as demonstrated by the ability of either thermal stimulation (50° C water) or subdermal …

Dynorphin-mediated antinociceptive effects of L-arginine and SIN-1 (an NO donor) in mice

E Chung, B Burke, AJ Bieber, JC Doss, Y Ohgami… - Brain research …, 2006 - Elsevier
The antinociceptive response of mice to the amino acid l-arginine (l-ARG) has been
attributed to either an opioid mechanism or a non-opioid but nitric oxide (NO)-dependent …

Nitrous oxide-antinociception is mediated by opioid receptors and nitric oxide in the periaqueductal gray region of the midbrain

DE Emmanouil, AS Dickens, RW Heckert… - European …, 2008 - Elsevier
Previous studies have shown that nitrous oxide (N2O)-induced antinociception is sensitive
to antagonism by blockade of opioid receptors and also by inhibition of nitric oxide (NO) …

The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats

GS Galdino, CH Xavier, R Almeida, G Silva… - International Journal …, 2015 - Taylor & Francis
Resistance exercise (RE) is characterized to increase strength, tone, mass, and/or muscular
endurance and also for produces many beneficial effects, such as blood pressure and …

The neuronal NO synthase participation in the peripheral antinociception mechanism induced by several analgesic drugs

TRL Romero, LC Resende, IDG Duarte - Nitric Oxide, 2011 - Elsevier
The production of nitric oxide (NO) from l-arginine is catalyzed by NO synthase (NOS), which
exists as the following three isoforms: endothelial (eNOS), neuronal (nNOS), and inducible …

GABAergic interneurons at supraspinal and spinal levels differentially modulate the antinociceptive effect of nitrous oxide in Fischer rats

R Orii, Y Ohashi, S Halder, M Giombini… - The Journal of the …, 2003 - pubs.asahq.org
Background The study hypothesizes that nitrous oxide (N (2) O) releases opioid peptide in
the brain stem, which results in inhibition of gamma-aminobutyric acid-mediated …

Nitric oxide/cyclic guanosine monophosphate system in the spinal cord differentially modulates intracerebroventricularly administered morphine-and beta-endorphin …

JY Xu, LF Tseng - Journal of Pharmacology and Experimental …, 1995 - ASPET
Our study was designed to study the modulatory role of nitric oxide/cyclic guanosine
monophosphate in the spinal cord on the antinociception induced by morphine and beta …

Different mechanisms mediate development and expression of tolerance and dependence for peripheral μ-opioid antinociception in rat

KO Aley, JD Levine - Journal of Neuroscience, 1997 - Soc Neuroscience
The μ-opioid [d-Ala2, N-Me-Phe4, Gly-ol5]-enkephalin (DAMGO) exerts a peripheral
antinociceptive effect against prostaglandin E2 (PGE2)-induced mechanical hyperalgesia in …

Role of guanylyl cyclase activation via thiamine in suppressing chemically-induced writhing in mouse

N Abacioğlu, S Demir, İ Çakici, B Tunçtan… - …, 2000 - thieme-connect.com
The possible role of L-arginine/nitric oxide (L-arginine/NO) pathway in the antinociceptive
activity of thiamine (vitamin B 1 in p-benzoquinone-induced mouse writhing model was …