The aging process induces a plethora of changes in the body including alterations in
hormonal regulation and metabolism in various organs including the heart. Aging is …

Remote ischemic preconditioning (RIPC) is an intrinsic phenomenon whereby 3~ 4
consecutive ischemia-reperfusion cycles to a remote tissue (noncardiac) increases the …

Protection against ischemia by ischemic preconditioning (IP) is seen in many tissues and
organs. However, the preconditioning ischemia must precede lethal ischemia for this effect …

The existing literature indicates a crucial role of p38 MAP (mitogen-activated protein) kinase
(p38MAPK) and its downstream target MAPKAP kinase 2 (MK2) in ischemic preconditioning …

Myocardial ischemia is a condition in which the coronary blood flow to the heart is reduced,
which results in deficient oxygen and nutrients supply to the heart. Reperfusion to an …

Adenosine is a naturally occurring breakdown product of adenosine triphosphate and plays
an important role in different physiological and pathological conditions. Adenosine also …

Objectives In animal studies, remote ischemic preconditioning (RIPC) is a powerful tool to
protect the heart from ischemia and reperfusion injury. Unfortunately, this effect was not seen …

Objective To explore the effects of ischemic postconditioning on ischemia/reperfusion injury
in isolated hypertrophied rat heart and investigate the signal transduction pathway changes …

Aims Since mitogen-activated protein kinases (MAPKs) were found to be implicated in the
signalling of ischaemic preconditioning (IPC), we tested the hypothesis of a contribution of …

Pre-, post-, and remote conditioning of the myocardium are well described adaptive
responses that markedly enhance the ability of the heart to withstand a prolonged …