Mouse models of follicular and papillary thyroid cancer progression

MA Russo, VGA Arciuch, A Di Cristofano - Frontiers in Endocrinology, 2012 - frontiersin.org
A significant number of well-differentiated thyroid cancers progress or recur, becoming
resistant to current therapeutic options. Mouse models recapitulating the genetic and …

[HTML][HTML] Preclinical models of follicular cell-derived thyroid cancer: an overview from cancer cell lines to mouse models

MJ Jeon, BR Haugen - Endocrinology and Metabolism, 2022 - synapse.koreamed.org
The overall prognosis of thyroid cancer is excellent, but some patients have grossly invasive
disease and distant metastases with limited responses to systemic therapies. Thus, relevant …

Mouse models of thyroid cancer: A 2015 update

LS Kirschner, Z Qamri, S Kari, A Ashtekar - Molecular and Cellular …, 2016 - Elsevier
Thyroid cancer is the most common endocrine neoplasm, and its rate is rising at an alarming
pace. Thus, there is a compelling need to develop in vivo models which will not only enable …

Development of novel follicular thyroid cancer models which progress to poorly differentiated and anaplastic thyroid cancer

CO Caperton, LA Jolly, N Massoll, AJ Bauer, AT Franco - Cancers, 2021 - mdpi.com
Simple Summary Advancements in thyroid cancer are dependent on the availability of
experimental models allowing for investigation in the laboratory setting. Here, we detail the …

Mouse Models to Examine Differentiated Thyroid Cancer Pathogenesis: Recent Updates

HR Choi, K Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Although the overall prognosis of differentiated thyroid cancer (DTC), the most common
endocrine malignancy, is favorable, a subset of patients exhibits aggressive features …

Overview of genetically engineered mouse models of papillary and anaplastic thyroid cancers: enabling translational biology for patient care improvement

RP Charles - Current protocols in pharmacology, 2015 - Wiley Online Library
The prognosis from thyroid cancer subtypes in humans covers a spectrum from “cured at
almost 90%” to “100% lethal.” Invasive and poorly differentiated forms of thyroid cancer are …

Modeling thyroid cancer in the mouse

XG Zhu, SY Cheng - Hormone and metabolic research, 2009 - thieme-connect.com
Thyroid carcinomas, the most common endocrine tumors in humans, have an increasing
incidence in the US and worldwide. There are four major types of thyroid cancers: papillary …

Thyroid cancer cell lines: critical models to study thyroid cancer biology and new therapeutic targets

RE Schweppe - Frontiers in endocrinology, 2012 - frontiersin.org
Thyroid cancer is the most common endocrine malignancy and the incidence is rising.
Currently, there are no effective treatments for patients with advanced forms of thyroid …

Development of Novel Murine BRAFV600E-Driven Papillary Thyroid Cancer Cell Lines for Modeling of Disease Progression and Preclinical Evaluation of …

GP Branigan, V Casado-Medrano, AB O'Neill… - Cancers, 2023 - mdpi.com
Simple Summary Laboratory experimental models are essential for advancements in thyroid
cancer translational research. In this study, we discuss the development and …

Lessons from mouse models of thyroid cancer

CS Kim, X Zhu - Thyroid, 2009 - liebertpub.com
Background: Thyroid cancer is the most common endocrine tumor and is increasing in
incidence. The aim of this study was to review mouse models of differentiated thyroid cancer …